ReviewEpilepsia2018
National Association of Medical Examiners position paper: Recommendations for the investigation and certification of deaths in people with epilepsy.
Review in Epilepsia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Mortality in patients with epilepsy: a systematic review.Journal of neurology · 2025Pooled it
- 2020 APHRS/HRS expert consensus statement on the investigation of decedents with sudden unexplained death and patients with sudden cardiac arrest, and of their families.Heart rhythm · 2021Guideline
- Systematic Review of the Genetics of Sudden Unexpected Death in Epilepsy: Potential Overlap With Sudden Cardiac Death and Arrhythmia-Related Genes.Journal of the American Heart Association · 2020Pooled it
- Article
- Mortality and mortality disparities among people with epilepsy in the United States, 2011-2021.Epilepsy & behavior : E&B · 2024Article
- Sudden unexpected death in epilepsy: A critical view of the literature.Epilepsia open · 2023Review
- Confirmation of Cause of Death Via Comprehensive Autopsy and Whole Exome Molecular Sequencing in People With Epilepsy and Sudden Unexpected Death.Journal of the American Heart Association · 2021Article
- Review: Neuropathology findings in autonomic brain regions in SUDEP and future research directions.Autonomic neuroscience : basic & clinical · 2021Review
- 2020 APHRS/HRS expert consensus statement on the investigation of decedents with sudden unexplained death and patients with sudden cardiac arrest, and of their families.Journal of arrhythmia · 2021Article
- Why are epilepsy mortality rates rising in the United States? A population-based multiple cause-of-death study.BMJ open · 2020Article
- CDC-supported epilepsy surveillance and epidemiologic studies: A review of progress since 1994.Epilepsy & behavior : E&B · 2020Review
- Serotonin and sudden unexpected death in epilepsy.Experimental neurology · 2020Review
- Sudden Unexplained Death in Childhood: A Neuropathology Review.Frontiers in neurology · 2020Review
- Risk Factors for Sudden Unexpected Death in Epilepsy (SUDEP) and Their Mitigation.Current treatment options in neurology · 2019Review
- [Genetic testing to prevent sudden cardiac death].Der Internist · 2018Review
- SUDEP: When the Nightmare Becomes the Reality.Epilepsy currentsArticle
Corrections and comments
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Authors and funding
17 authors.
Funding
Abstract
Sudden unexpected death of an individual with epilepsy can pose a challenge to death investigators, as most deaths are unwitnessed, and the individual is commonly found dead in bed. Anatomic findings (eg, tongue/lip bite) are commonly absent and of varying specificity, thereby limiting the evidence to implicate epilepsy as a cause of or contributor to death. Thus it is likely that death certificates significantly underrepresent the true number of deaths in which epilepsy was a factor. To address this, members of the National Association of Medical Examiners, North American SUDEP Registry, Epilepsy Foundation SUDEP Institute, American Epilepsy Society, and the Centers for Disease Control and Prevention constituted an expert panel to generate evidence-based recommendations for the practice of death investigation and autopsy, toxicological analysis, interpretation of autopsy and toxicology findings, and death certification to improve the precision of death certificate data available for public health surveillance of epilepsy-related deaths. The recommendations provided in this paper are intended to assist medical examiners, coroners, and death investigators when a sudden unexpected death in a person with epilepsy is encountered.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.