Evidence map›Paper›PMID 29492713›Full record

ArticleLasers in medical science2018

Fractional CO

Angelamaria Becorpi, Giuseppina Campisciano, Nunzia Zanotta, Zelinda Tredici, Secondo Guaschino, Felice Petraglia, Annalisa Pieralli, Giovanni Sisti, Francesco De Seta, Manola Comar

Registry-linked trialOpen access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Lasers in medical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05585476 (Effectiveness of C02 Microfractionated Laser in Conjunction With Topical Regenerative Therapy in the Management of Vulvo-vaginal Atrophy in Patients With a History of Breast Cancer. Randomized Experimental and Comparative Study.), which is not on this map. Cited by 37 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 4 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05585476 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Effectiveness of C02 Microfractionated Laser in Conjunction With Topical Regenerative Therapy in the Management of Vulvo-vaginal Atrophy in Patients With a History of Breast Cancer. Randomized Experimental and Comparative Study.

TypeinterventionalSponsorInstituto de Investigación Sanitaria de la Fundación Jiménez DíazRan2025 to 2026Enrolled180ConditionsFemale Urogenital Diseases, Breast Cancer FemaleArmsC02 microablative laser, Regenerative topical treatment
3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 4 syntheses or guidelines pooled it, 67 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Vaginal pixel CO2 laser versus topical use of promestriene for genitourinary syndrome of menopause.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2026
    Trial
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Addressing the Needs of Breast Cancer Survivors.Current oncology reports · 2025
    Review
  14. Efficacy of Erbium and COLasers in surgery and medicine · 2025
    Article
  15. Review
  16. COCancers · 2025
    Article
  17. Review
  18. Understanding the Benefits of COMedicina (Kaunas, Lithuania) · 2024
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Angelamaria BecorpiSection of Gynecology and Obstetrics, Department of Woman and Child Health, Careggi University Hospital, Largo Brambilla 3, 50144, Florence, Italy.
Giuseppina CampiscianoInstitute for Maternal and Child Health-IRCCS "Burlo Garofolo", via dell'Istria 65/1, 34100, Trieste, Italy.
Nunzia ZanottaInstitute for Maternal and Child Health-IRCCS "Burlo Garofolo", via dell'Istria 65/1, 34100, Trieste, Italy.
Zelinda TrediciSection of Gynecology and Obstetrics, Department of Woman and Child Health, Careggi University Hospital, Largo Brambilla 3, 50144, Florence, Italy.
Secondo GuaschinoSection of Gynecology and Obstetrics, Department of Woman and Child Health, Careggi University Hospital, Largo Brambilla 3, 50144, Florence, Italy.
Felice PetragliaSection of Gynecology and Obstetrics, Department of Woman and Child Health, Careggi University Hospital, Largo Brambilla 3, 50144, Florence, Italy.
Annalisa PieralliSection of Gynecology and Obstetrics, Department of Woman and Child Health, Careggi University Hospital, Largo Brambilla 3, 50144, Florence, Italy.
Giovanni SistiSection of Gynecology and Obstetrics, Department of Woman and Child Health, Careggi University Hospital, Largo Brambilla 3, 50144, Florence, Italy.
Francesco De SetaInstitute for Maternal and Child Health-IRCCS "Burlo Garofolo", via dell'Istria 65/1, 34100, Trieste, Italy.
Manola ComarInstitute for Maternal and Child Health-IRCCS "Burlo Garofolo", via dell'Istria 65/1, 34100, Trieste, Italy. manola.comar@burlo.trieste.it.
Azienda Ospedaliero-Universitaria Careggi · ITIRCCS Materno Infantile Burlo Garofolo · ITUniversity of Trieste · IT

Funding

Ministero della Salute RC 26/13
6 · The paper itself

Abstract

The composition of vaginal microbiome in menopause and cancer survivor women changes dramatically leading to genitourinary syndrome of menopause (GSM) in up to 70% of patients. Recent reports suggest that laser therapy may be valuable as a not hormonal therapeutic modality. The aim of the present study was to evaluate the effects of fractional CO

Indexed as

Breast NeoplasmsCancer SurvivorsCytokinesDyspareuniaFemaleHumansLasers, GasMenopauseMicrobiotaMiddle AgedProspective StudiesSyndromeVaginaVaginal DiseasesCytokinesBreast cancerCytokines/chemokinesFractional CO2 laserMenopauseMicrobiome

Identifiers

PMID29492713
OpenAlexW2792262594

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.