Evidence map›Paper›PMID 29492645›Full record

ReviewJournal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry2018

The role of zinc and its compounds in leukemia.

Alexey P Orlov, Marina A Orlova, Tatiana P Trofimova, Stepan N Kalmykov, Dmitry A Kuznetsov

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 33 citations in OpenAlex.

  1. Trace Elements in Medicinal Metallomics.Mini reviews in medicinal chemistry · 2025
    Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Advances of Zinc Signaling Studies in Prostate Cancer.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Alexey P OrlovChemical Department, Lomonosov Moscow State University, 1, Bd. 3 Leninskie Gory, 119992, Moscow, Russia. orlova.radiochem@mail.ru.
Marina A OrlovaChemical Department, Lomonosov Moscow State University, 1, Bd. 3 Leninskie Gory, 119992, Moscow, Russia.
Tatiana P TrofimovaChemical Department, Lomonosov Moscow State University, 1, Bd. 3 Leninskie Gory, 119992, Moscow, Russia.
Stepan N KalmykovChemical Department, Lomonosov Moscow State University, 1, Bd. 3 Leninskie Gory, 119992, Moscow, Russia.
Dmitry A KuznetsovPirogov Russian National Research Medical University, 1, Ostrovityanova st., 117997, Moscow, Russia.
Lomonosov Moscow State University · RUPirogov Russian National Research Medical University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zinc is one of the most important microelements necessary for normal body functioning. Zinc is marked in numerous diseases and, hence, its properties and behavior in the body have long been a subject of extensive study. This review considers trends in the assessment of the role of zinc and its compounds in the past decade. It becomes evident that redox-inactive zinc is the main supervisor in the conformation of the most important molecules in all body organs and tissues. We placed emphasis on the variety of zinc-binding sites and the role of zinc in the genesis and progress of different forms of leukemia. The importance of some families of transcription factors in the development and prognosis of treatment of various leukemia forms is examined; new directions of these studies are shown.

Indexed as

Binding SitesHomeostasisHumansLeukemiaTranscription FactorsZincZinc CompoundsTranscription FactorsZincZinc CompoundsMetallothioneinsSignaling pathwayZincZinc chelationZinc complexesZinc fingersZinc salicylates

Identifiers

PMID29492645
OpenAlexW2793683826

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.