ArticleInternational journal of reproductive biomedicine2017
Successful pregnancy and live birth after intrauterine administration of autologous platelet-rich plasma in a woman with recurrent implantation failure: A case report.
Article in International journal of reproductive biomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 52 citations in OpenAlex.
- Spontaneous pregnancy following intra-ovarian platelet-rich plasma administration in poor ovarian responders according to the POSEIDON criteria: A cross-sectional study.International journal of reproductive biomedicine · 2025Article
- Novel therapeutic strategies for Asherman's syndrome: Endometrial regeneration using menstrual blood-derived stem cells.Regenerative therapy · 2025Review
- Effects of autologous platelet-rich plasma intrauterine perfusion on clinical outcomes in recurrent implantation failure patients with non-thin endometrium undergoing frozen-thawed embryo transfer.Archives of gynecology and obstetrics · 2025Article
- Evaluation of adding autologous platelet-rich plasma to embryo transfer media on implantation outcomes: An RCT.International journal of reproductive biomedicine · 2025Article
- Effectiveness of Autologous Platelet-Rich Plasma Therapy in Women with Repeated Implantation Failure: A Randomized Clinical Trial.International journal of fertility & sterility · 2024Article
- Thrombocytes and Platelet-Rich Plasma as Modulators of Reproduction and Fertility.International journal of molecular sciences · 2023Review
- Clinical Application of Platelet Concentrates in Bovine Practice: A Systematic Review.Veterinary sciences · 2023Review
- How Does Platelet-Rich Plasma Injection in Ovaries of Poor Responders Affect the Retrieved Oocytes, and Anti Mullerian Hormone: A Clinical Trial.Journal of family & reproductive health · 2023Article
- Effects of Intrauterine Infusion of Autologous Platelet-Rich Plasma in Women Undergoing Treatment with Assisted Reproductive Technology: a Meta-Analysis of Randomized Controlled Trials.Geburtshilfe und Frauenheilkunde · 2023Article
- Efficacy of Platelet-Rich Plasma in Women with a History of Embryo Transfer Failure: A Systematic Review and Meta-Analysis with Trial Sequential Analysis.Bioengineering (Basel, Switzerland) · 2023Review
- Platelet-Rich Plasma Improves Pregnancy Outcomes in Moderate to Severe Intrauterine Adhesion: A Retrospective Cohort Study.Journal of clinical medicine · 2023Article
- Analysis of pregnancy outcomes in patients with recurrent implantation failure complicated with chronic endometritis.Frontiers in cell and developmental biology · 2023Article
- Cell-based therapy in thin endometrium and Asherman syndrome.Stem cell research & therapy · 2022Review
- A narrative review of platelet-rich plasma (PRP) in reproductive medicine.Journal of assisted reproduction and genetics · 2021Review
- Platelet-rich plasma (PRP) therapy: An approach in reproductive medicine based on successful animal models.Animal reproduction · 2020Article
- Article
- Using autologous intrauterine platelet-rich plasma to improve the reproductive outcomes of women with recurrent implantation failure.JBRA assisted reproduction · 2020Article
- Intrauterine Infusion of Human Platelet-Rich Plasma Improves Endometrial Regeneration and Pregnancy Outcomes in a Murine Model of Asherman's Syndrome.Frontiers in physiology · 2020Article
- New therapeutic protocol for improvement of endometrial receptivity (PRIMER) for patients with recurrent implantation failure (RIF) - A pilot study.JBRA assisted reproduction · 2019Article
- A report on three live births in women with poor ovarian response following intra-ovarian injection of platelet-rich plasma (PRP).Molecular biology reports · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPlatelets contain a significant amount of growth factors that have positive effects on local tissue repair and endometrial receptivity. CASE: Here we present a 45-yr-old woman with primary infertility and two failed in vitro fertilization (IVF) cycles who was candidate to receive donor eggs. Five consecutive frozen-thawed embryo transfer cycles with good quality embryos were performed within 2 yr. With the diagnosis of recurrent implantation failure (RIF), the patient was treated for improving endometrial receptivity with intrauterine administration of autologous platelet-rich plasma (PRP), 24 hr before embryo transfer. The patient gave birth to a healthy baby boy weighing 2350 gr in the cesarean section.
conclusionExtensive literature search suggests that this is the first successful pregnancy after administration of PRP in a woman with RIF. Local administration of PRP before embryo transfer may play a vital role in successful implantation .
Indexed as
Identifiers
29492478PMC5816241W2786292085What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.