Evidence map›Paper›PMID 29492468›Full record

ReviewLaryngoscope investigative otolaryngology2018

Systematic review of the diagnostic value of magnetic resonance imaging for early glottic carcinoma.

Sylvia L van Egmond, Inge Stegeman, Frank A Pameijer, Johanna J Bluemink, Chris H Terhaard, Luuk M Janssen

Abstract readReview
In one paragraph

Review in Laryngoscope investigative otolaryngology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Glottic tumours involving the anterior commissure in a horizontal vs vertical mode have different prognosis. Opportunity for refinement of the TNM 8Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2026
    Review
  2. Diagnostic value of MRI for posttreatment surveillance of early-stage (I-II) glottic larynx cancer.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026
    Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sylvia L van EgmondDepartment of Otorhinolaryngology and Head & Neck Surgery UMC Cancer Center University Medical Center Utrecht Utrecht The Netherlands.ORCID 0000-0003-2394-5982
Inge StegemanDepartment of Otorhinolaryngology and Head & Neck Surgery UMC Cancer Center University Medical Center Utrecht Utrecht The Netherlands.
Frank A PameijerDepartment of Radiology UMC Cancer Center University Medical Center Utrecht Utrecht The Netherlands.
Johanna J BlueminkDepartment of Radiotherapy UMC Cancer Center University Medical Center Utrecht Utrecht The Netherlands.
Chris H TerhaardDepartment of Radiotherapy UMC Cancer Center University Medical Center Utrecht Utrecht The Netherlands.
Luuk M JanssenDepartment of Head and Neck Surgical Oncology UMC Cancer Center University Medical Center Utrecht Utrecht The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: In early glottic cancer, accurate assessment of tumor extension, including depth infiltration, is of great importance for both staging, therapeutic approach and systematic comparison of data. Our goal was to assess the diagnostic value of MRI in pre-therapeutic staging of primary early stage (T1 and T2) glottic carcinoma. Study design: Systematic review of literature. Methods: We conducted a systematic search in Pubmed, Embase, and Scopus up to September 23, 2016. Included studies were selected and critically appraised for relevance and validity. Results: Seven out of 938 unique articles were selected, including 64 cases. MRI over-staged 6% and under-staged 13% of cT1 and cT2 tumors. However, available data is heterogeneous, very limited and mainly based on subanalysis of a small amount of patients. Reported MRI protocols appear to be suboptimal for small laryngeal lesions. Diagnostic value of MRI for subtle depth infiltration or laryngeal anatomical subsites (eg, laryngeal ventricle, vocal cord, etc.) could not be assessed. Conclusions: More studies are needed to assess the diagnostic value of MRI for small glottic tumors.

Indexed as

early glottic carcinomaMRIpretherapeutic staging

Identifiers

PMID29492468
PMCPMC5824105

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.