Evidence map›Paper›PMID 29492398›Full record

ArticleResearch and reports in urology2018

Prostatic artery embolization versus transurethral resection of the prostate in the treatment of benign prostatic hyperplasia: protocol for a non-inferiority clinical trial.

Saturnino Napal Lecumberri, Iñigo Insausti Gorbea, Ana Sáez de Ocáriz García, Saioa Solchaga Álvarez, José Luis Cebrián Lostal, Raquel Monreal Beortegui, Pedro José Giral Villalta, Fermín Urtasun Grijalba

Open access · goldAbstract read
In one paragraph

Article in Research and reports in urology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Prostatic Artery Embolization: Indications, Preparation, Techniques, Imaging Evaluation, Reporting, and Complications.Radiographics : a review publication of the Radiological Society of North America, Inc
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Saturnino Napal LecumberriServicio de Urología.
Iñigo Insausti GorbeaSección de Radiología Vascular Intervencionista, Complejo Hospitalario de Navarra, Pamplona, Navarra, Spain.
Ana Sáez de Ocáriz GarcíaSección de Radiología Vascular Intervencionista, Complejo Hospitalario de Navarra, Pamplona, Navarra, Spain.
Saioa Solchaga ÁlvarezSección de Radiología Vascular Intervencionista, Complejo Hospitalario de Navarra, Pamplona, Navarra, Spain.
José Luis Cebrián LostalServicio de Urología.
Raquel Monreal BeorteguiSección de Radiología Vascular Intervencionista, Complejo Hospitalario de Navarra, Pamplona, Navarra, Spain.
Pedro José Giral VillaltaServicio de Urología.
Fermín Urtasun GrijalbaSección de Radiología Vascular Intervencionista, Complejo Hospitalario de Navarra, Pamplona, Navarra, Spain.
Complejo Hospitalario de Navarra · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBenign prostatic hyperplasia (BPH) is a prevalent disease associated with lower urinary tract symptoms (LUTS). The standard of care for moderate-to-severe LUTS unresponsive to pharmacological treatment is the transurethral resection of the prostate (TURP). However, this intervention is not exempt from complications. Prostatic artery embolization (PAE) has been described as a new, effective and safe procedure for the treatment of LUTS secondary to BPH. To date, only one clinical trial has been published on the use of PAE for LUTS, but the study was methodologically flawed in terms of safety monitoring. Therefore, well-designed clinical studies are required to compare the efficacy and safety of both techniques in the treatment of LUTS secondary to BPH. METHODS AND

designThis was a prospective, randomized, non-inferiority clinical trial comparing efficacy and safety of PAE and TURP in the treatment of BPH-related LUTS. A total of 60 patients diagnosed with BPH with obstructive moderate or severe LUTS refractory to medical therapy and candidates for TURP were randomized to either PAE or TURP. The presence and severity of LUTS were assessed using the validated Spanish version of the International Prostate Symptom Score (IPSS). Primary end points included improvement in maximum urinary flow rate ( DISCUSSION: The aim of this clinical study was to investigate whether PAE is a valid therapeutic option for LUTS that is not inferior to TURP in terms of efficacy and safety. This study also helped to define the profile of candidates for PAE and analyzed the benefits and complications associated with this new technique.

Indexed as

benign prostatic hyperplasiaclinical triallower urinary tract symptomsprostatic artery embolizationtransurethral resection of the prostate

Identifiers

PMID29492398
PMCPMC5815502
OpenAlexW2789842800

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.