ArticleAnnals of cardiothoracic surgery2018
Transplantation in the single ventricle population.
Article in Annals of cardiothoracic surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 47 citations in OpenAlex.
- Clinical Deterioration in Stage 1 and 2 Single Ventricle Patients Awaiting Heart Transplant: A Single Center Experience.Pediatric cardiology · 2026Article
- Late Total Cavopulmonary Connection in Adolescents and Adults: Narrative Review of Patient Selection and Outcomes.Journal of cardiovascular development and disease · 2026Review
- Outcomes of Heart Transplantation in Single-Ventricle Physiology: A Retrospective Single-Center Experience with Emphasis on Surgical Complexity.Journal of clinical medicine · 2026Article
- Long-term outcomes of heart transplantation in adults with congenital heart disease: The impact of single-ventricle versus biventricular physiology.JTCVS open · 2024Article
- Long-Term Survival After Single-Ventricle Palliation: A Swedish Nationwide Cohort Study.Journal of the American Heart Association · 2024Article
- The potential of cardiac xenotransplantation for management of infants with complex congenital heart disease.Translational pediatrics · 2023Review
- Cardiac transplantation in adult congenital heart disease: a narrative review.Journal of thoracic disease · 2023Review
- Ex Vivo Modeling of Atrioventricular Valve Mechanics in Single Ventricle Physiology.Annals of biomedical engineering · 2023Article
- A Novel Strategy for the Mechanical Subpulmonary Support in Failing Fontan Patients.The Thoracic and cardiovascular surgeon · 2022Article
- Transplant and mechanical circulatory support in patients with adult congenital heart disease.Heart failure reviews · 2020Review
- Proceedings From the 2019 Stanford Single Ventricle Scientific Summit: Advancing Science for Single Ventricle Patients: From Discovery to Clinical Applications.Journal of the American Heart Association · 2020Article
- Heart failure in single right ventricle congenital heart disease: physiological and molecular considerations.American journal of physiology. Heart and circulatory physiology · 2020Review
- Analysis of Congenital Heart Defects in Mouse Embryos Using Qualitative and Quantitative Histological Methods.Journal of visualized experiments : JoVE · 2020Article
- Current spectrum, challenges and new developments in the surgical care of adults with congenital heart disease.Cardiovascular diagnosis and therapy · 2018Review
- Heart Transplantation and Mechanical Circulatory Support in Adults with Congenital Heart Disease.Current cardiology reports · 2018Review
- A Decision Rule for Determining the Optimal Transplant Listing Window for Patients With a Fontan Physiology.MDM policy & practiceArticle
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The single ventricle patient population comprises the most complex cohort presenting to the cardiac transplant team, in terms of demographics, anatomic substrate, and unique physiology. It is also the most rapidly growing diagnostic group presenting for heart transplantation. In this manuscript, we aim to describe the changing landscape of transplantation in single ventricle conditions through reflection on our own institution's practice and experience, alongside contemporary literature review. Single ventricle patients are heterogeneous in terms of age, anatomic diagnosis and physiology according to surgical stage of repair. Progress in surgical palliative strategies has impacted upon the present composition of the population, with growing numbers of hypoplastic left heart syndrome patients and those with late physiology failure following Fontan completion. Multiple prior surgeries, immunological sensitivity and multi-organ involvement impart high peri-operative risk but can be mitigated in part by careful pre-operative planning by a dedicated multi-disciplinary team addressing issues such as planning of concurrent reconstructive surgery, minimizing the post-operative effect of collaterals, timely harvesting, oversizing of donor organs to minimize graft failure, and strategies to address anticipated post-operative elevation in pulmonary vascular resistance. Determining optimal timing for transplant in these patients remains unclear, but understanding the risk of alternative surgical options can help guide decision making with regards to listing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.