Evidence map›Paper›PMID 29492381›Full record

ReviewAnnals of cardiothoracic surgery2018

Percutaneous coronary intervention versus coronary artery bypass grafting in heart transplant recipients with coronary allograft vasculopathy: a systematic review and meta-analysis of 1,520 patients.

Jessica G Y Luc, Jae Hwan Choi, Syed-Saif Abbas Rizvi, Kevin Phan, Ester Moncho Escrivà, Sinal Patel, Gordon R Reeves, Andrew J Boyle, John W Entwistle, Rohinton J Morris and 2 more

Open access · diamondAbstract readReview
In one paragraph

Review in Annals of cardiothoracic surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Coronary Artery Vasculopathy in a Cohort of Heart Transplant Recipients: A Single Center Experience.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025
    Article
  7. Single-cell RNA-sequencing identifies unique cell-specific gene expression profiles in high-grade cardiac allograft vasculopathy.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2025
    Article
  8. Article
  9. Everolimus-eluting stents versus sirolimus-eluting stents in patients with cardiac allograft vasculopathy.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2021
    Article
  10. Review
  11. Drug-eluting balloon: is it useful?The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2020
    Review
  12. Outcomes following cardiac transplantation in adults.Indian journal of thoracic and cardiovascular surgery · 2020
    Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 4 countries.

Jessica G Y LucFaculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Jae Hwan ChoiDivision of Cardiac Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Syed-Saif Abbas RizviDivision of Cardiac Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Kevin PhanFaculty of Medicine, University of New South Wales, Sydney, Australia.
Ester Moncho EscrivàDepartment of Statistics, University of Granada, Granada, Spain.
Sinal PatelDivision of Cardiac Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Gordon R ReevesDivision of Cardiology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Andrew J BoyleDivision of Cardiology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
John W EntwistleDivision of Cardiac Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Rohinton J MorrisDivision of Cardiac Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
H Todd MasseyDivision of Cardiac Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Vakhtang TchantchaleishviliDivision of Cardiac Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Thomas Jefferson University · USUniversidad de Granada · ESUniversity of Alberta · CAUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTransplant coronary artery vasculopathy (TCAV) is the major cause of late allograft failure and death in heart transplant recipients. The aim of this systematic review was to examine the outcomes of percutaneous coronary interventions (PCIs) as compared to coronary artery bypass grafting (CABG) surgery in the management of TCAV. Our secondary objective was to compare the use and outcomes of drug eluting stents (DES) as compared to bare metal stents (BMS) in this patient population.

methodsElectronic search was performed to identify all studies in the English literature examining PCI as compared to CABG for TCAV in heart transplant recipients. All identified articles were systematically assessed for inclusion and exclusion criteria.

resultsOf the 4,989 studies identified, 29 studies were included. Among 1,520 patients who developed TCAV, 1,470 patients underwent PCI and 50 patients underwent CABG. There were no significant differences in baseline demographics and comorbidities among the PCI and CABG cohorts. Compared to the PCI cohort, patients who underwent CABG had a higher early mortality (CABG 36.4%

conclusionsCABG and PCI are both feasible modalities for revascularization in patients with TCAV where PCI is associated with lower mortality. There were no differences in outcomes among patients who underwent PCI with DES as compared to BMS. Potential bias may exist due to heterogeneity in available data. Further studies are needed to delineate evidence-based guidelines to tailor the appropriate therapy, CABG or PCI, to the appropriate patient.

Indexed as

coronary artery bypass grafting (CABG)heart transplantationPercutaneous coronary interventions (PCIs)revascularizationtransplant coronary allograft vasculopathy

Identifiers

PMID29492381
PMCPMC5827131
OpenAlexW2785698305

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.