ArticleEnvironmental epigenetics2016
Transcriptomic data reanalysis allows for a contribution of embryonic transcriptional change-induced gene expression reprogramming in transgenerational epigenetic inheritance.
Article in Environmental epigenetics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed, 4 citations in OpenAlex.
- A systematic scientometric review of paternal inheritance of acquired metabolic traits.BMC biology · 2023Review
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1 author at 1 institution in 1 country.
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Abstract
A recent study investigated sperm-mediated inheritance of diet induced metabolic phenotypes, reported underlying regulation of the target genes of the endogenous retroelement MERVL and the ribosomal protein genes in embryos, and suggested that the altered regulation observed may cause placentation defects which can secondarily result in abnormal metabolism. A reanalysis of available transcriptomic data however shows that MERVL targets and the developmentally altered genes are themselves enriched for metabolic pathways, thus connecting embryonic gene expression with offspring phenotypes, and providing an alternative interpretation of the reported findings. This is consistent with a similar study suggesting a contribution of embryonic transcriptional change-induced gene expression reprogramming in altered offspring metabolism.
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