Evidence map›Paper›PMID 29492238›Full record

ReviewOncotarget2018

Anorectal mucosal melanoma.

Giulia Malaguarnera, Roberto Madeddu, Vito Emanuele Catania, Gaetano Bertino, Luca Morelli, Rosario Emanuele Perrotta, Filippo Drago, Michele Malaguarnera, Saverio Latteri

Open access · diamondAbstract readReview
In one paragraph

Review in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
2.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 99 citations in OpenAlex.

  1. Article
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  4. Primary melanoma of the gastrointestinal tract.World journal of gastroenterology · 2026
    Review
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  19. Review
  20. Anorectal mucosal melanoma.Seminars in colon & rectal surgery · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Giulia MalaguarneraResearch Center "The Great Senescence", University of Catania, Catania, Italy.
Roberto MadedduDepartment of Biomedical Sciences, University of Sassari, Sassari, Italy.
Vito Emanuele CataniaDepartment of Medical, Surgical Sciences and Advanced Technologies "G.F. Ingrassia", University of Catania, Catania, Italy.
Gaetano BertinoHepatology Unit, Department of Clinical and Experimental Medicine, University of Catania, Policlinico "G. Rodolico", Catania, Italy.
Luca MorelliDepartment of Surgery, University of Pisa, Pisa, Italy.
Rosario Emanuele PerrottaDepartment of General Surgery and Medical-Surgery Specialties, University of Catania, Catania, Italy.
Filippo DragoDepartment of Biomedical and Biotechnological Science, University of Catania, Catania, Italy.
Michele MalaguarneraResearch Center "The Great Senescence", University of Catania, Catania, Italy.
Saverio LatteriDepartment of Medical, Surgical Sciences and Advanced Technologies "G.F. Ingrassia", University of Catania, Catania, Italy.
University of Catania · ITUniversity of Pisa · ITUniversity of Sassari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anorectal melanoma is an uncommon and aggressive mucosal melanocytic malignancy. Due to its rarity, the pre-operative diagnosis remains difficult. The first symptoms are non-specific such as anal bleeding, anal mass or pain. Although anorectal melanoma carries a poor prognosis; optimal therapeutics strategies are unclear. Surgical resection remains the mainstay of treatment. The optimal surgical procedure for primary tumours is controversial and can vary from wide local excision or endoscopic mucosal resection (EMR) to an abdomino-perineal resection. A high degree of uncertainly exists regarding the benefit of radiation therapy or chemotherapy. The treatment of advanced melanoma is evolving rapidly with better understanding of the disease biology and immunology. Considerable effort has been devoted to the identification of molecular determinants of response to target therapies and immunotherapy.

Indexed as

anorectal melanomaanorectal tumoursmalignant melanomamucosal melanomatreatment

Identifiers

PMID29492238
PMCPMC5823579
OpenAlexW2781995165

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.