Evidence map›Paper›PMID 29492214›Full record

ArticleOncotarget2018

Genetic alterations in main candidate genes during melanoma progression.

Maria Cristina Sini, Valentina Doneddu, Panagiotis Paliogiannis, Milena Casula, Maria Colombino, Antonella Manca, Gerardo Botti, Paolo A Ascierto, Amelia Lissia, Antonio Cossu and 1 more

Abstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Primary Melanoma of the Lung: A Systematic Review.Medicina (Kaunas, Lithuania) · 2020
    Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Strategy of combining CDK4/6 inhibitors with other therapies and mechanisms of resistance.International journal of clinical and experimental pathology · 2024
    Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Maria Cristina SiniUnit of Cancer Genetics, Institute of Biomolecular Chemistry, National Research Council, Sassari, Italy.
Valentina DonedduDepartment of Surgical, Microsurgical and Medical Sciences, University of Sassari, Sassari, Italy.
Panagiotis PaliogiannisDepartment of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy.
Milena CasulaUnit of Cancer Genetics, Institute of Biomolecular Chemistry, National Research Council, Sassari, Italy.
Maria ColombinoUnit of Cancer Genetics, Institute of Biomolecular Chemistry, National Research Council, Sassari, Italy.
Antonella MancaUnit of Cancer Genetics, Institute of Biomolecular Chemistry, National Research Council, Sassari, Italy.
Gerardo BottiIstituto Nazionale Tumori, Fondazione Pascale, Napoli, Italy.
Paolo A AsciertoIstituto Nazionale Tumori, Fondazione Pascale, Napoli, Italy.
Amelia LissiaDepartment of Surgical, Microsurgical and Medical Sciences, University of Sassari, Sassari, Italy.
Antonio CossuDepartment of Surgical, Microsurgical and Medical Sciences, University of Sassari, Sassari, Italy.
Giuseppe PalmieriUnit of Cancer Genetics, Institute of Biomolecular Chemistry, National Research Council, Sassari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cutaneous melanoma is a common and aggressive human skin cancers. Much is actually known about the molecular mechanisms underlying melanoma pathogenesis. The aim of the study was to evaluate any possible correlation between mutations in main growth-controlling genes (

Indexed as

fluorescence in situ hybridization (FISH) analysisgenetic heterogeneitymalignant melanomamutation analysisoncogenic driver genes

Identifiers

PMID29492214
PMCPMC5823576

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.