Evidence map›Paper›PMID 29492183›Full record

ReviewOxidative medicine and cellular longevity2018

Honey as a Potential Natural Antioxidant Medicine: An Insight into Its Molecular Mechanisms of Action.

Sarfraz Ahmed, Siti Amrah Sulaiman, Atif Amin Baig, Muhammad Ibrahim, Sana Liaqat, Saira Fatima, Sadia Jabeen, Nighat Shamim, Nor Hayati Othman

Open access · hybridAbstract readReview
In one paragraph

Review in Oxidative medicine and cellular longevity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed, 1 pooled it
26.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 1 synthesis or guideline pooled it, 334 citations in OpenAlex.

  1. Pooled it
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  15. Ecological, Apicultural, and Therapeutic Value ofFoods (Basel, Switzerland) · 2025
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47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Sarfraz AhmedDepartment of Pathology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, 16150 Kelantan, Malaysia.
Siti Amrah SulaimanDepartment of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, 16150 Kelantan, Malaysia.
Atif Amin BaigFaculty of Medicine, Universiti Sultan Zainal Abidin, Darul Iman, Kuala Terengganu, 20400 Terengganu, Malaysia.
Muhammad IbrahimDepartment of Biochemistry, Bahauddin Zakariya University, Multan 60800, Pakistan.
Sana LiaqatDepartment of Biochemistry, Bahauddin Zakariya University, Multan 60800, Pakistan.
Saira FatimaDepartment of Biochemistry, Bahauddin Zakariya University, Multan 60800, Pakistan.
Sadia JabeenDepartment of Biochemistry, Bahauddin Zakariya University, Multan 60800, Pakistan.
Nighat ShamimDepartment of Biochemistry, Bahauddin Zakariya University, Multan 60800, Pakistan.
Nor Hayati OthmanDepartment of Pathology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, 16150 Kelantan, Malaysia.ORCID 0000-0002-8640-5740
Bahauddin Zakariya University · PKUniversiti Sains Malaysia · MYSultan Zainal Abidin University · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Honey clasps several medicinal and health effects as a natural food supplement. It has been established as a potential therapeutic antioxidant agent for various biodiverse ailments. Data report that it exhibits strong wound healing, antibacterial, anti-inflammatory, antifungal, antiviral, and antidiabetic effects. It also retains immunomodulatory, estrogenic regulatory, antimutagenic, anticancer, and numerous other vigor effects. Data also show that honey, as a conventional therapy, might be a novel antioxidant to abate many of the diseases directly or indirectly associated with oxidative stress. In this review, these wholesome effects have been thoroughly reviewed to underscore the mode of action of honey exploring various possible mechanisms. Evidence-based research intends that honey acts through a modulatory road of multiple signaling pathways and molecular targets. This road contemplates through various pathways such as induction of caspases in apoptosis; stimulation of TNF-

Indexed as

HoneyAnimalsAntioxidantsHumansAntioxidants

Identifiers

PMID29492183
PMCPMC5822819
OpenAlexW2784913868

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.