ArticlePakistan journal of medical sciences
Neutrophil lymphocyte ratio (NLR): A well assessment tool of glycemic control in type 2 diabetic patients.
Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
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Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 81 citations in OpenAlex.
- The Association between Neutrophil-to-Lymphocyte Ratio and Glycemic Control in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis.Journal of diabetes research · 2023Pooled it
- Effects of neutrophil-to-lymphocyte ratio, serum calcium, and serum albumin on prognosis in patients with diabetic foot.International wound journal · 2023Trial
- Neutrophil-Linked Inflammatory Mechanisms and Biomarkers in Diabetic Microvascular Complications.Diabetes & metabolism journal · 2026Review
- Neutrophil Gelatinase-Associated Lipocalin and Neutrophil-to-Lymphocyte Ratio as Indicators of Nephropathy in Type 2 Diabetic Mellitus Patients in Ghana: A Case-Control Study.Health science reports · 2026Article
- Exploring the Relationship Between Neutrophil-to-Lymphocyte Ratio and Glycemic Control in Type 2 Diabetes Mellitus: A Cross-Sectional Analysis.Journal of clinical medicine · 2026Article
- Comparative Longitudinal Evaluation of Systemic Inflammatory Markers in Type 2 Diabetes Treated with Four Oral Antidiabetic Drug Classes.Journal of clinical medicine · 2026Article
- Serum C-reactive protein and C-reactive protein derived markers in diabetic microvascular complications.World journal of diabetes · 2025Review
- Article
- Association Between Pentraxins and Obesity in Prediabetes and Newly Diagnosed Type 2 Diabetes Mellitus Patients.International journal of molecular sciences · 2025Article
- Evaluation of Complete Blood Count Parameters in Patients With Diabetes Mellitus: A Systematic Review.Health science reports · 2025Review
- Evaluation of Hematological Parameters in Diabetic Patients.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2025Article
- Blood indices of inflammation and their association with hypertension in smokers: analysis using data mining approaches.Journal of human hypertension · 2025Article
- The correlation between plasma lactoferrin and inflammatory biomarkers in type 2 diabetes with dry eye disease patients.Frontiers in medicine · 2025Article
- Overexpression of Chromatin Remodeling Factor SRG3 Down-Regulates IL1β-Expressing M1 Macrophages and IL17-Producing T Cells in Adipose Tissues.International journal of molecular sciences · 2024Article
- Inflammation indices in association with periodontitis and cancer.Periodontology 2000 · 2024Review
- Correlation between neutrophil to lymphocyte ratio and C-reactive protein in diverse disease states in hospitalized patients.Pakistan journal of medical sciences · 2024Article
- Article
- The association between the neutrophil-to-lymphocyte ratio and type 2 diabetes mellitus: a cross-sectional study.BMC endocrine disorders · 2024Article
- Association of systemic inflammatory indices with anthropometric measures, metabolic factors, and liver function in non-alcoholic fatty liver disease.Scientific reports · 2024Article
- Assessment of the systemic immune-inflammation index in type 2 diabetic patients with and without dry eye disease: A case-control study.Health science reports · 2024Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectiveIncreased neutrophil lymphocyte ratio (NLR) is a marker as well as predictor of various cardiac and non cardiac disorders. Our aim was to assess the relationship between NLR and different level of glycemic control in type 2 diabetic patients.
methodsAn observational study was conducted at diabetic clinic of Sheikh Zayed Medical College/Hospital, Rahim Yar Khan from September 2016 to February 2017 in which 330 type 2 diabetic patients were randomly divided in to three groups based upon diabetes control according to ADA criteria. Patients in group A with HbA1c ≤ 7% (excellent control), group B HbA1c 7.0-9.0 % (poor control) and group C HbA1c ≥ 9 %(worst control). Patients were assessed in terms of complete blood count and C - reactive protein.
resultsAs compared to excellent control (Group A) patients with worst control (Group C)showed a high leukocyte count (p.001), high neutrophil count (P.003) and lower lymphocyte count (P 0.44) while patients in poor control (Group B)did not differ significantly. Similarly value of NLR was also significantly higher in worst control (Group C) as compared to poor control(Group B) and excellent control (Group A) diabetes (4.3±2.8, 2.7±1.0 and2.0±0.5(p.001). NLR were found independent predictor of worst diabetes control (OR: 1.809, 95% CI: 1.459-2.401) along with fasting blood sugar (OR: 0.938, 95% CI: 0.995-0.982) and CRP (OR: 1.020, 95% CI: 1.003-1.028).
conclusionIncreased NLR level is associated with elevated HbA1c and poor glycemic control in patients of type 2 diabetes mellitus. It can be used as a disease monitoring tool during the follow up of diabetic patients.
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