Evidence map›Paper›PMID 29491687›Full record

Observational studyWorld journal of gastroenterology2018

Comparison of

Hong-Hui Wang, Ying He, Hong-Xian Wang, Cheng-Ling Liao, Yu Peng, Li-Jian Tao, Wei Zhang, Hui-Xiang Yang

Open access · hybridAbstract readComparative StudyObservational Study
In one paragraph

Observational study in World journal of gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Review
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  6. Medical sciences (Basel, Switzerland) · 2025
    Review
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  18. Meta-Analysis ofFrontiers in pharmacology · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Hong-Hui WangDepartment of Gastroenterology, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China.
Ying HeDepartment of Gastroenterology, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China.
Hong-Xian WangDepartment of Anesthesiology, Kunming Angel Women's & Children's Hospital, Kunming 650000, Yunnan Province, China.
Cheng-Ling LiaoDepartment of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China.
Yu PengDepartment of Gastroenterology, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China.
Li-Jian TaoDepartment of Nephrology, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China.
Wei ZhangDepartment of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China.
Hui-Xiang YangDepartment of Gastroenterology, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China. yang_hx430@csu.edu.cn.
Central South University · CNXiangya Hospital Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo observe gene polymorphisms of

methodsThis study enrolled 219 patients diagnosed with IBD in Xiangya Hospital, Central South University, Changsha, China from February 2016 to November 2017. Peripheral blood of all patients was collected to detect their genotypes of

resultsThere were 219 patients with IBD (160 men and 59 women), including 39 who were confirmed with ulcerative colitis (UC), 176 with Crohn's disease (CD) and 4 with undetermined IBD (UIBD). There were 44 patients (20.1%) with mutant genotype of

conclusionMutation rate of

Indexed as

AdultAsian PeopleAzathioprineBiomarkersCohort StudiesFemaleGenotyping TechniquesHumansInflammatory Bowel DiseasesLeukopeniaMaleMethyltransferasesMiddle AgedMutationNudix HydrolasesPolymorphism, GeneticAzathioprineBiomarkersMethyltransferasesNudix HydrolasesNUDT15 protein, humanPyrophosphatasesthiopurine methyltransferaseTPMT protein, humanAzathioprineIndividualized therapyInflammatory bowel diseaseLeukopeniaNUDT15TPMT

Identifiers

PMID29491687
PMCPMC5829157
OpenAlexW2788213183

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.