Evidence map›Paper›PMID 29491568›Full record

ArticleJournal of parasitic diseases : official organ of the Indian Society for Parasitology2018

Assessment of spiramycin-loaded chitosan nanoparticles treatment on acute and chronic toxoplasmosis in mice.

Samia E Etewa, Dalia A Abo El-Maaty, Rania S Hamza, Ashraf S Metwaly, Mohamed H Sarhan, Sara A Abdel-Rahman, Ghada M Fathy, Mahmoud A El-Shafey

Open access · greenAbstract read
In one paragraph

Article in Journal of parasitic diseases : official organ of the Indian Society for Parasitology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 77 citations in OpenAlex.

  1. Article
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  10. Modulation of CXCL10 activity as a therapeutic target of ocular toxoplasmosis in diabetic mice.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Use of nanoparticles, a modern means of drug delivery, against cryptosporidiosis.Journal of advanced veterinary and animal research · 2023
    Review
  15. Review
  16. Effects ofFood and waterborne parasitology · 2023
    Article
  17. Ivermectin modulated cerebral γ-aminobutyric acid (GABA) and reduced the number of chronicJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2023
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Samia E Etewa1Medical Parasitology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Dalia A Abo El-Maaty1Medical Parasitology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Rania S Hamza1Medical Parasitology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Ashraf S Metwaly1Medical Parasitology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Mohamed H Sarhan1Medical Parasitology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Sara A Abdel-Rahman1Medical Parasitology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Ghada M Fathy1Medical Parasitology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Mahmoud A El-Shafey2Clinical Pathology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Zagazig University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toxoplasmosis is a zoonotic parasitic disease with worldwide distribution. Chitosan is a natural polymer which is commonly used in the production of nanomedicines. It is known to enable higher drug permeation, being biocompatible and has very low toxicity, besides its antimicrobial effects. Our study aimed to assess the effect of spiramycin-loaded chitosan nanoparticles (SLCNs) in treatment of acute and chronic toxoplasmosis in mice. 200 male Swiss albino mice were included in our study, divided to two main groups;

Indexed as

HistopathologyNanoparticlesspiramycinToxoplasmosisTreatment

Identifiers

PMID29491568
PMCPMC5825375
OpenAlexW2772765913

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.