Evidence map›Paper›PMID 29491538›Full record

ReviewReumatologia

Antinuclear antibodies in autoimmune and allergic diseases.

Bogna Grygiel-Górniak, Natalia Rogacka, Michał Rogacki, Mariusz Puszczewicz

Open access · diamondAbstract readReview
In one paragraph

Review in Reumatologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Bogna Grygiel-GórniakDepartment of Rheumatology and Internal Diseases, Poznan University of Medical Sciences, Poland.
Natalia RogackaDepartment of Rheumatology and Internal Diseases, Poznan University of Medical Sciences, Poland.
Michał RogackiNZOZ Alergo-Med, Outpatient Clinic Poznan, Poland.
Mariusz PuszczewiczDepartment of Rheumatology and Internal Diseases, Poznan University of Medical Sciences, Poland.
Poznan University of Medical Sciences · PLNZOZ Centrum Alergologii · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antinuclear antibodies (ANA) are primarily significant in the diagnosis of systemic connective tissue diseases. The relationship between their occurrence in allergic diseases is poorly documented. However, the mechanism of allergic and autoimmune diseases has a common thread. In both cases, an increased production of IgE antibodies and presence of ANA in selected disease entities is observed. Equally important is the activation of basophils secreting proinflammatory factors and affecting the differentiation of TH17 lymphocytes. Both autoimmune and allergic diseases have complex multi-pathogenesis and often occur in genetically predisposed individuals. The presence of antinuclear antibodies was confirmed in many systemic connective tissue diseases and some allergic diseases. Examples include atopic dermatitis, non-allergic asthma, and pollen allergy. Co-occurring allergic and autoimmune disorders induce further search for mechanisms involved in the aetiopathogenesis of both groups of diseases.

Indexed as

allergyantinuclear antibodiesautoimmune diseasesmolecular background

Identifiers

PMID29491538
PMCPMC5825968
OpenAlexW2784777066

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.