ArticleScientific reports2018
The circadian regulator BMAL1 programmes responses to parasitic worm infection via a dendritic cell clock.
Open access · goldAbstract read
In one paragraph
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
5.2field-weighted citation impact, top 3% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed, 80 citations in OpenAlex.
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- Clockwork intruders: Do parasites manipulate their hosts' circadian rhythms?Current research in parasitology & vector-borne diseases · 2024Review
- Immunological and inflammatory effects of infectious diseases in circadian rhythm disruption and future therapeutic directions.Molecular biology reports · 2023Review
- Diurnal changes and topographical distribution of ocular surface epithelial dendritic cells in humans, and repeatability of density and morphology assessment.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2023Article
- Influence of circadian clocks on adaptive immunity and vaccination responses.Nature communications · 2023Article
- The circadian clock influences T cell responses to vaccination by regulating dendritic cell antigen processing.Nature communications · 2022Article
- Circadian rhythms mediate infection risk inEcology and evolution · 2022Article
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Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 2 institutions in 1 country.
Thomas W HopwoodFaculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester, M13 9PT, UK.
Sarah HallFaculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester, M13 9PT, UK.
Nicola BegleyFaculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester, M13 9PT, UK.
Ruth FormanFaculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester, M13 9PT, UK.
Sheila BrownManchester Collaborative Centre for Inflammation Research, University of Manchester, Manchester, M13 9NT, UK.
Ryan VonslowFaculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester, M13 9PT, UK.
Ben SaerFaculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester, M13 9PT, UK.
Matthew C LittleFaculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester, M13 9PT, UK.
Emma A MurphyFaculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester, M13 9PT, UK.
Rebecca J HurstFaculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester, M13 9PT, UK.
David W RayFaculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester, M13 9PT, UK.ORCID 0000-0002-4739-6773
Andrew S MacDonaldManchester Collaborative Centre for Inflammation Research, University of Manchester, Manchester, M13 9NT, UK.ORCID 0000-0002-5356-1149
Andy BrassFaculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester, M13 9PT, UK.
David A BechtoldFaculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester, M13 9PT, UK.ORCID 0000-0001-8676-8704
Julie E GibbsFaculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester, M13 9PT, UK. julie.gibbs@manchester.ac.uk.
Andrew S LoudonFaculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester, M13 9PT, UK. Andrew.loudon@manchester.ac.uk.
Kathryn J ElseFaculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester, M13 9PT, UK. Kathryn.j.else@manchester.ac.uk.
Manchester Academic Health Science Centre · GBUniversity of Manchester · GB
Funding
Arthritis Research UK 20629Biotechnology and Biological Sciences Research CouncilMedical Research Council MR/L018640/1Medical Research Council MR/M008908/1Medical Research Council MR/N022661/1Medical Research Council MR/P023576/1Wellcome TrustWellcome Trust 091815Wellcome Trust 107849/Z/15/ZWellcome Trust 107851/Z/15/Z
Abstract
Resistance to the intestinal parasitic helminth Trichuris muris requires T-helper 2 (T
Indexed as
Circadian RhythmAnimalsARNTL Transcription FactorsCells, CulturedDendritic CellsLymph NodesMaleMiceMice, Inbred C57BLMice, KnockoutTh2 CellsT-LymphocytesTrichuriasisTrichurisARNTL Transcription FactorsBmal1 protein, mouse
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.