Evidence map›Paper›PMID 29491134›Full record

ArticleGenes & development2018

A rADAR defense against RNAi.

Amy E Pasquinelli

Open access · diamondAbstract readComment
In one paragraph

Article in Genes & development, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

  • Comment on
    2018
5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Amy E PasquinelliDivision of Biology, University of California at San Diego, La Jolla, California 92093, USA.
University of California, San Diego · US

Funding

Role of Argonaute in miRNA biogenesis and functionR01GM071654 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PASQUINELLI, AMY E. · 2004 to 2017
$4.0M
Role of miRNA Argonautes in organismal agingR01AG056562 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PASQUINELLI, AMY E. · 2017 to 2021
$1.9M
NIA NIH HHS R01 AG056562NIGMS NIH HHS R01 GM071654
6 · The paper itself

Abstract

Adenosine deaminases that act on RNA (ADARs) convert adenosines (A) to inosines (I) in stretches of dsRNA. The biological purpose of these editing events for the vast majority of ADAR substrates is largely unknown. In this issue of

Indexed as

Antiviral AgentsAnimalsCaenorhabditis elegansRadarRNA, Double-StrandedRNA EditingRNA InterferenceAntiviral AgentsRNA, Double-StrandeddeaminaseDicerRNA editingself–nonselfsiRNA

Identifiers

PMID29491134
PMCPMC5859962
OpenAlexW2789737059

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.