Evidence map›Paper›PMID 29491131›Full record

ArticleGut2019

Plasma ghrelin is probably not a useful biomarker for risk prediction or early detection of colorectal cancer.

Anneli Sundkvist, Robin Myte, Richard Palmqvist, Sophia Harlid, Bethany Van Guelpen

Abstract readLetterComment
In one paragraph

Article in Gut, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Genome-Wide Association and Two-Sample Mendelian Randomization Analyses of Plasma Ghrelin and Gastrointestinal Cancer Risk.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023
    Pooled it
  2. Article
  3. Plasma Ghrelin and Risks of Sex-Specific, Site-Specific, and Early-Onset Colorectal Cancer: A Mendelian Randomization Analysis.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Article
  4. Article
  5. Role of the Ghrelin System in Colorectal Cancer.International journal of molecular sciences · 2022
    Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Obesity and the Risk of Gastrointestinal Cancers.Digestive diseases and sciences · 2019
    Review
  11. Review
  12. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Anneli SundkvistDepartment of Radiation Sciences, Oncology Unit, Umeå University, Umea, Sweden.ORCID 0000-0002-6679-6414
Robin MyteDepartment of Radiation Sciences, Oncology Unit, Umeå University, Umea, Sweden.
Richard PalmqvistDepartment of Medical Biosciences, Pathology Unit, Umeå University, Umeå, Sweden.
Sophia HarlidDepartment of Radiation Sciences, Oncology Unit, Umeå University, Umea, Sweden.
Bethany Van GuelpenDepartment of Radiation Sciences, Oncology Unit, Umeå University, Umea, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Colorectal NeoplasmsGhrelinAdenocarcinomaBiomarkers, TumorEarly Detection of CancerHumansBiomarkers, TumorGhrelincancercolorectal cancerepidemiologygastrointestinal hormones

Identifiers

PMID29491131
PMCPMC6352395

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.