Evidence map›Paper›PMID 29490972›Full record

ArticleJournal of the American Heart Association2018

Left Ventricular Torsion Associated With Aortic Stiffness in Hypertension.

Jean-Barthelemy Gnakamene, Michel E Safar, Bernard I Levy, Brigitte Escoubet

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Association of Nondiabetic Glucometabolic Status and Aortic Stiffness in Community Hypertension Patients.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Jean-Barthelemy GnakameneDepartment of Physiology, Hôpital Bichat, Assistance Publique-Hôpitaux de Paris, Paris, France jb.gnakamene@gmail.com.
Michel E SafarCentre de Diagnostic et Thérapeutique Cardiovasculaire, Hôpital Hôtel-Dieu, Assistance Publique-Hôpitaux de Paris, Paris, France.
Bernard I LevyINSERM U-970, Centre de Recherches Cardiovasculaire, Paris, France.
Brigitte EscoubetDepartment of Physiology, Hôpital Bichat, Assistance Publique-Hôpitaux de Paris, Paris, France.
Centre de Recherche des Cordeliers · FRHôpital Bichat-Claude-Bernard · FRHôpital Lariboisière · FRUniversité Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLeft ventricular (LV) torsion plays a key role in cardiac efficiency. In hypertension, aortic stiffening augments cardiac afterload. However, little is known about the links between LV regional contraction and aortic stiffness. We, therefore, investigated these relationships and their contribution to LV diastolic function. METHODS AND

resultsThe study included normotensive and hypertensive individuals with normal LV ejection. Apical, basal, and global LV rotation rate and LV global longitudinal strain were measured (2-dimensional speckle tracking echocardiography). Aortic stiffness was calculated from carotid-femoral pulse wave velocity, and LV relaxation was calculated from early diastolic mitral annulus motion. The ratio of basal or apical untwist/twist rates was calculated to assess relationships between aortic stiffness and LV torsion parameters. LV twist and untwist rates were greater in hypertensive than normotensive individuals because of increased basal twist (

conclusionsIn hypertensive individuals, greater basal LV torsion was associated with increased aortic stiffness and improved diastolic function. These changes may compensate for the deleterious effects of aortic stiffening on LV relaxation.

Indexed as

Vascular StiffnessVentricular Function, LeftAdaptation, PhysiologicalAdultAgedArterial PressureBiomechanical PhenomenaCase-Control StudiesDiastoleEchocardiography, DopplerFemaleHumansHypertensionMaleMiddle AgedPulse Wave Analysisaortic stiffnesshypertensionleft ventricular torsion

Identifiers

PMID29490972
PMCPMC5866318
OpenAlexW2790945857

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.