Evidence map›Paper›PMID 29490667›Full record

ArticleBMC research notes2018

Research priorities during infectious disease emergencies in West Africa.

Morenike Oluwatoyin Folayan, Bridget Haire, Dan Allman, Aminu Yakubu, Muhammed O Afolabi

Abstract read
In one paragraph

Article in BMC research notes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Morenike Oluwatoyin FolayanInstitute of Public Health, Obafemi Awolowo University, Ile-Ife, Nigeria. toyinukpong@yahoo.co.uk.ORCID http://orcid.org/0000-0002-9008-7730
Bridget HaireKirby Institute, University of New South Wales, Sydney, Australia.
Dan AllmanDalla Lana School of Public Health, University of Toronto, Toronto, Canada.
Aminu YakubuFederal Ministry of Health, Abuja, Nigeria.
Muhammed O AfolabiDepartment of Clinical Research, London School of Hygiene & Tropical Medicine, London, UK.

Funding

Wellcome TrustWellcome Trust 202969/Z/16/Z
6 · The paper itself

Abstract

objectivesThis paper presents the results of the consultations conducted with various stakeholders in Africa and other experts to document community perspectives on the types of research to be prioritised in outbreak conditions. The Delphi method was used to distill consensus.

resultsOur consultations highlighted as key, the notion that in an infectious disease outbreak situation, the need to establish an evidence base on how to reduce morbidity and mortality in real time takes precedence over the production of generalizable knowledge. Research studies that foster understanding of how disease transmission could be prevented in the future remain important, implementation research that explores how to mitigate the impact of outbreaks in the present should be prioritized. Clinical trials aiming to establish the safety profile of therapeutic interventions should be limited during the acute phase of an epidemic with high fatality-and should preferably use adaptive designs. We concluded that community members have valuable perspectives to share about research priorities during infectious disease emergencies. Well designed consultative processes could help identify these opinions.

Indexed as

Biomedical ResearchClinical Trials as TopicCommunicable Disease ControlResearch DesignCommunicable DiseasesDelphi TechniqueDisease OutbreaksEmergenciesHumansConsultationEpidemicInfectious diseaseResearch designResearch prioritiesWest Africa

Identifiers

PMID29490667
PMCPMC5831857

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.