A Role for Hydrocortisone Therapy in Septic Shock?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. Impact and Beneficial Critical Points of Clinical Outcome in Corticosteroid Management of Adult Patients With Sepsis: Meta-Analysis and GRADE Assessment.Frontiers in pharmacology · 2019
   Pooled it
2. Polymyxin B hemoperfusion in endotoxemic septic shock patients without extreme endotoxemia: a post hoc analysis of the EUPHRATES trial.Intensive care medicine · 2018
   Trial
3. CytoSorb® Hemoadsorption as a Promising Tool to Handle COVID-19-Induced Cytokine Storm.Case reports in critical care · 2021
   Article
4. Hydrocortisone Reduces 28-day Mortality in Septic Patients: A Systemic Review and Meta-analysis.Cureus · 2019
   Article
5. A current appraisal of evidence for the approach to sepsis and septic shock.Therapeutic advances in infectious disease
   Review

Corrections and comments

• Comment on
  Adjunctive Glucocorticoid Therapy in Patients with Septic Shock.2018

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as