ArticleMedicine2018
A case report of POEMS syndrome with renal involvement as immunotactoid glomerulopathy.
Article in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 4 citations in OpenAlex.
- Efficacy of novel agents in patients with nephropathy associated with POEMS syndrome.International urology and nephrology · 2022Article
- POEMS Syndrome with Biclonal Gammopathy and Renal Involvement.Internal medicine (Tokyo, Japan) · 2022Article
- Renal Diseases Associated with Hematologic Malignancies and Thymoma in the Absence of Renal Monoclonal Immunoglobulin Deposits.Diagnostics (Basel, Switzerland) · 2021Review
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
rationalePOEMS syndrome is a rare multi-system disorder, which sometimes involves the kidney. Immunotactoid glomerulopathy (ITG) is an uncommon glomerular disease resulted from deposits of immunoglobulins and its derivatives. ITG caused by POEMS syndrome is rarely reported. PATIENT CONCERNS: A 63-year-old man was presented with acute kidney injury. In addition, it's found that he had abnormal serum free κ /λ ratio, polyneuropathy, Castleman's disease, organomegaly, endocrinopathy and skin changes. DIAGNOSES: POEMS syndrome was diagnosed, Renal biopsy revealed an ITG.
interventionsDexamethasone and thalidomide were given, as well as hemodialysis and other supportive treatments. OUTCOMES: The patient's extrarenal manifestations improved gradually and his renal function also showed slight improvement. LESSONS: ITG caused by POEMS syndrome is rare, however, it makes sense that the monoclonal proteins produced by the plasma cells could cause ITG. Chemotherapy similar to that employed in multiple myeloma may be beneficial for these patients.
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Registered trials
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