Evidence map›Paper›PMID 29489663›Full record

SynthesisMedicine2018

MRI and CT contrast media extravasation: A systematic review.

Ashkan Heshmatzadeh Behzadi, Zerwa Farooq, Jeffery H Newhouse, Martin R Prince

Registry-linked trialAbstract readSystematic Review
In one paragraph

Synthesis in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04397029 (Assessing the Sensitivity of "SureTouch™" in Identifying Clinically Significant Masses in Women Undergoing Diagnostic and Screening Mammography), which is not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04397029 naterminatednot on this mapstarted 2019, after this paper: background citation

Assessing the Sensitivity of "SureTouch™" in Identifying Clinically Significant Masses in Women Undergoing Diagnostic and Screening Mammography

TypeinterventionalSponsorGeorge Washington UniversityRan2019 to 2021Enrolled213ConditionsBreast CancerArmsSureTouch
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  16. Dual-energy CT in pulmonary vascular disease.The British journal of radiology · 2022
    Review
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  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ashkan Heshmatzadeh BehzadiDepartment of Radiology, Weill Cornell Medicine Department of Radiology, Columbia College of Physicians and Surgeons, New York, NY.
Zerwa Farooq
Jeffery H Newhouse
Martin R Prince

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis systematic review combines data from multiple papers on contrast media extravasation to identify factors contributing to increased extravasation risk.

methodsData were extracted from 17 papers reporting 2191 extravasations in 1,104,872 patients (0.2%) undergoing computed tomography (CT) or magnetic resonance imaging (MRI).

resultsExtravasation rates were 0.045% for gadolinium-based contrast agents (GBCA) and nearly 6-fold higher, 0.26% for iodinated contrast agents. Factors associated with increased contrast media extravasations included: older age, female gender, using an existing intravenous (IV) instead of placing a new IV in radiology, in-patient status, use of automated power injection, high injection rates, catheter location, and failing to warm up the more viscous contrast media to body temperature.

conclusionContrast media extravasation is infrequent but nearly 6 times less frequent with GBCA for MRI compared with iodinated contrast used in CT.

Indexed as

AdolescentAdultAgedAged, 80 and overChildChild, PreschoolContrast MediaExtravasation of Diagnostic and Therapeutic MaterialsFemaleHumansInfantMagnetic Resonance ImagingMaleMiddle AgedRisk FactorsTomography, X-Ray ComputedContrast Media

Identifiers

PMID29489663
PMCPMC5851722

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.