Evidence map›Paper›PMID 29489428›Full record

ArticleJournal of clinical oncology : official journal of the American Society of Clinical Oncology2018

Breast Cancer Diagnosis and Treatment After High-Deductible Insurance Enrollment.

J Frank Wharam, Fang Zhang, Christine Y Lu, Anita K Wagner, Larissa Nekhlyudov, Craig C Earle, Stephen B Soumerai, Dennis Ross-Degnan

Abstract read
In one paragraph

Article in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Impact of High Deductible Health Plans on Diabetes Care Quality and Outcomes: Systematic Review.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2021
    Pooled it
  2. Article
  3. What do health insurance deductibles do to health care spending growth?International journal of health economics and management · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

J Frank WharamJ. Frank Wharam, Fang Zhang, Christine Y. Lu, Anita K. Wagner, Stephen B. Soumerai, and Dennis Ross-Degnan, Harvard Medical School and Harvard Pilgrim Health Care Institute; Larissa Nekhlyudov, Dana-Farber Cancer Institute; Boston, MA; and Craig C. Earle, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
Fang ZhangJ. Frank Wharam, Fang Zhang, Christine Y. Lu, Anita K. Wagner, Stephen B. Soumerai, and Dennis Ross-Degnan, Harvard Medical School and Harvard Pilgrim Health Care Institute; Larissa Nekhlyudov, Dana-Farber Cancer Institute; Boston, MA; and Craig C. Earle, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
Christine Y LuJ. Frank Wharam, Fang Zhang, Christine Y. Lu, Anita K. Wagner, Stephen B. Soumerai, and Dennis Ross-Degnan, Harvard Medical School and Harvard Pilgrim Health Care Institute; Larissa Nekhlyudov, Dana-Farber Cancer Institute; Boston, MA; and Craig C. Earle, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
Anita K WagnerJ. Frank Wharam, Fang Zhang, Christine Y. Lu, Anita K. Wagner, Stephen B. Soumerai, and Dennis Ross-Degnan, Harvard Medical School and Harvard Pilgrim Health Care Institute; Larissa Nekhlyudov, Dana-Farber Cancer Institute; Boston, MA; and Craig C. Earle, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
Larissa NekhlyudovJ. Frank Wharam, Fang Zhang, Christine Y. Lu, Anita K. Wagner, Stephen B. Soumerai, and Dennis Ross-Degnan, Harvard Medical School and Harvard Pilgrim Health Care Institute; Larissa Nekhlyudov, Dana-Farber Cancer Institute; Boston, MA; and Craig C. Earle, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
Craig C EarleJ. Frank Wharam, Fang Zhang, Christine Y. Lu, Anita K. Wagner, Stephen B. Soumerai, and Dennis Ross-Degnan, Harvard Medical School and Harvard Pilgrim Health Care Institute; Larissa Nekhlyudov, Dana-Farber Cancer Institute; Boston, MA; and Craig C. Earle, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
Stephen B SoumeraiJ. Frank Wharam, Fang Zhang, Christine Y. Lu, Anita K. Wagner, Stephen B. Soumerai, and Dennis Ross-Degnan, Harvard Medical School and Harvard Pilgrim Health Care Institute; Larissa Nekhlyudov, Dana-Farber Cancer Institute; Boston, MA; and Craig C. Earle, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
Dennis Ross-DegnanJ. Frank Wharam, Fang Zhang, Christine Y. Lu, Anita K. Wagner, Stephen B. Soumerai, and Dennis Ross-Degnan, Harvard Medical School and Harvard Pilgrim Health Care Institute; Larissa Nekhlyudov, Dana-Farber Cancer Institute; Boston, MA; and Craig C. Earle, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.

Funding

High Deductible Insurance: Impact on Breast Cancer Care and OutcomesR01CA172639 · NCI · HARVARD PILGRIM HEALTH CARE, INC. · PI WHARAM, JAMES FRANKLIN · 2013 to 2017
$3.0M
NCI NIH HHS R01 CA172639
6 · The paper itself

Abstract

Purpose High-deductible health plans (HDHPs) require substantial out-of-pocket spending and might delay crucial health services. Breast cancer treatment delays of as little as 2 months are associated with adverse outcomes. Methods We used a controlled prepost design with survival analysis to assess timing of breast cancer care events among 273,499 women age 25 to 64 years without evidence of breast cancer before inclusion. Women were included if continuously enrolled for 1 year in a low-deductible ($0 to $500) plan followed by up to 4 years in a HDHP (at least $1,000 deductible) after an employer-mandated switch. Study inclusion was on a rolling basis, and members were followed between 2003 and 2012. The comparison group comprised 2.4 million contemporaneously matched women whose employers offered only low-deductible plans. Measures were times to first diagnostic breast imaging (diagnostic mammogram, breast ultrasound, or breast magnetic resonance imaging), breast biopsy, incident early-stage breast cancer diagnosis, and breast cancer chemotherapy. Outcomes were analyzed by using Cox models and adjusted for age-group, morbidity score, poverty level, US region, index date, and employer size. Results After the index date, HDHP members experienced delays in receipt of diagnostic imaging (adjusted hazard ratio [aHR], 0.95; 95% CI, 0.94 to 0.96), biopsy (aHR, 0.92; 95% CI, 0.89 to 0.95), early-stage breast cancer diagnosis (aHR, 0.83; 0.78 to 0.90), and chemotherapy initiation (aHR, 0.79; 95% CI, 0.72 to 0.86) compared with the control group. Conclusion Women switched to HDHPs experienced delays in diagnostic breast imaging, breast biopsy, early-stage breast cancer diagnosis, and chemotherapy initiation. Additional research should determine whether such delays cause adverse health outcomes, and policymakers should consider selectively reducing out-of-pocket costs for key breast cancer services.

Indexed as

Health Care CostsHealth ExpendituresAdultBiopsyBreast NeoplasmsDeductibles and CoinsuranceDelayed DiagnosisEarly Detection of CancerFemaleHumansInsurance CoverageInsurance, HealthMammographyMiddle AgedNeoplasm StagingPredictive Value of Tests

Identifiers

PMID29489428
PMCPMC5891127

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.