ReviewExpert review of anti-infective therapy2018
Syphilis incidence in men who have sex with men with human immunodeficiency virus comorbidity and the importance of integrating sexually transmitted infection prevention into HIV care.
Review in Expert review of anti-infective therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- The impact of the National Syphilis Prevention Program on the prevalence of syphilis among people living with HIV in China: a systematic review and meta-analysis.Journal of the International AIDS Society · 2025Pooled it
- Neurosyphilis presenting as status epilepticus and hemiplegia diagnosed by metagenomic next-generation sequencing: A case report.Experimental and therapeutic medicine · 2026Article
- Successful Scale-up of Syphilis Testing Linked to Routine HIV Viral Load Monitoring in British Columbia.Open forum infectious diseases · 2026Article
- Epidemiological characteristics of syphilis in China from 2005 to 2020: predominance of latent Infections, significant burden in the elderly population, and analysis of regional disparities.BMC public health · 2025Article
- Infectious Proctitis Mimicking Advanced Rectal Cancer: A Case Report and Update on the Differential Diagnosis of Rectal Ulcerations.Journal of clinical medicine · 2025Article
- Impact pathways of adverse childhood experiences on infectious diseases among substance abusers in border regions: structural equation modeling.Frontiers in public health · 2025Article
- Review
- Article
- Syphilis among HIV-positive men who have sex with men in Ghana: The 2023 biobehavioral survey.PloS one · 2024Article
- Prevalence, risk factors and treatment outcomes of syphilis among people living with human immunodeficiency virus at primary care clinics in Malaysia: A retrospective study.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2024Article
- Assessment of Visual Acuity Outcomes in Ocular Syphilis Treated With Adjunctive Topical or Oral Steroids.Cureus · 2023Article
- Neurosyphilis With Concomitant Respiratory Failure: A Case Study and Treatment Considerations.Cureus · 2023Article
- High Prevalence of Syphilis and Syphilis/HIV Coinfection among Men Who Have Sex with Men Who Attend Meeting Places in Mexico.Pathogens (Basel, Switzerland) · 2023Article
- Lifetime prevalence of syphilis infection among predominantly Black sexual and gender minorities living with HIV in Atlanta, Georgia: a cross-sectional analysis.Ethnicity & health · 2023Article
- Risk Factors and Incidence of Sexually Transmitted Infections in the Swiss HIV Cohort Study.Open forum infectious diseases · 2022Article
- Prevalence of syphilis and risk factors among HIV-positive men who have sex with men in Guangdong province.Frontiers in public health · 2022Article
- LGBTQ+ health research guides at North American health sciences libraries: a survey and content analysis.Journal of the Medical Library Association : JMLA · 2021Article
- Patient perspectives on the implementation of routinised syphilis screening with HIV viral load testing: Qualitative process evaluation of the Enhanced Syphilis Screening Among HIV-positive Men trial.BMC health services research · 2021Article
- Syphilitic infection impairs immunity by inducing both apoptosis and pyroptosis of CD4Innate immunity · 2021Article
- Pilot implementation of a home-care programme with chlamydia, gonorrhoea, hepatitis B, and syphilis self-sampling in HIV-positive men who have sex with men.BMC infectious diseases · 2020Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
introductionSyphilis continues to be a growing epidemic among men who have sex with men (MSM), particularly for those living with the human immunodeficiency virus (HIV). In 2016, MSM accounted for 80% of primary and secondary syphilis diagnoses in men in the United States; almost half of who were also HIV-infected. The synergistic relationship between HIV and syphilis has significant implications not only for HIV patient management, but also for sexually transmitted infection (STI) control among MSM. Areas covered: We review the literature on STI screening and treatment barriers at the patient-, provider-, and health system-levels, and present strategies to incorporate STI prevention into HIV care settings. Expert commentary: Integration of STI prevention into HIV care is paramount to stop the epidemic of not only syphilis, but also other curable STIs like gonorrhea and chlamydia. Although guidelines have been established for STI testing in HIV-infected MSM, screening rates continue to be lower than desired. Gonorrhea and chlamydia screening is below 50% in HIV-infected MSM; interventions that improve testing of those two infections must be implemented. For syphilis control, other additional strategies such as chemoprophylaxis should be considered given syphilis screening is above 50% in HIV-infected MSM.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.