Evidence map›Paper›PMID 29489362›Full record

ArticleJournal of the American Chemical Society2018

Primary Transfer Step in the Light-Driven Ion Pump Bacteriorhodopsin: An Irreversible U-Turn Revealed by Dynamic Nuclear Polarization-Enhanced Magic Angle Spinning NMR.

Qing Zhe Ni, Thach V Can, Eugenio Daviso, Marina Belenky, Robert G Griffin, Judith Herzfeld

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
5.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 69 citations in OpenAlex.

  1. Review
  2. Article
  3. Diamond rotors for high magic angle spinning frequencies.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Resonant Mixing Dynamic Nuclear Polarization.The journal of physical chemistry letters · 2023
    Article
  9. Biradical Polarizing Agents at High Fields.The journal of physical chemistry. B · 2022
    Article
  10. Observation of a four-spin solid effect.The Journal of chemical physics · 2022
    Article
  11. Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  12. DNPSOUP: A simulation software package for dynamic nuclear polarization.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2022
    Review
  13. Solid-State NMR Spectroscopy on Microbial Rhodopsins.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  14. Article
  15. O to bR transition in bacteriorhodopsin occurs through a proton hole mechanism.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  16. Time domain DNP at 1.2 T.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2021
    Article
  17. Article
  18. Solid-state NMR spectroscopy.Nature reviews. Methods primers · 2021
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Qing Zhe NiDepartment of Chemistry and Francis Bitter Magnet Laboratory , Massachusetts Institute of Technology , 77 Massachusetts Avenue , Cambridge , Massachusetts 02139 , United States.
Thach V CanDepartment of Chemistry and Francis Bitter Magnet Laboratory , Massachusetts Institute of Technology , 77 Massachusetts Avenue , Cambridge , Massachusetts 02139 , United States.
Eugenio DavisoDepartment of Chemistry and Francis Bitter Magnet Laboratory , Massachusetts Institute of Technology , 77 Massachusetts Avenue , Cambridge , Massachusetts 02139 , United States.
Marina BelenkyDepartment of Chemistry , Brandeis University , Waltham , Massachusetts 02454 , United States.
Robert G GriffinDepartment of Chemistry and Francis Bitter Magnet Laboratory , Massachusetts Institute of Technology , 77 Massachusetts Avenue , Cambridge , Massachusetts 02139 , United States.ORCID 0000-0003-1589-832X
Judith HerzfeldDepartment of Chemistry , Brandeis University , Waltham , Massachusetts 02454 , United States.
Massachusetts Institute of Technology · USBrandeis University · US

Funding

OverallP41EB002026 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI GRIFFIN, ROBERT GUY · 2003 to 2018
$17.9M
High Field DNP in Biological SystemsR01EB002804 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI GRIFFIN, ROBERT GUY · 2003 to 2018
$9.1M
Solid State NMR Studies of Membrane ProteinsR01EB001960 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI GRIFFIN, ROBERT GUY · 2003 to 2017
$6.5M
High Field DNP and EPR in Biological SystemsR01GM132997 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI GRIFFIN, ROBERT GUY · 2019 to 2025
$4.6M
TR&D 4 -- Advanced Magic Angle Spinning NMR methodsP41GM132079 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI GRIFFIN, ROBERT GUY · 2019 to 2021
$3.6M
NMR STUDIES OF BIOLOGICAL MEMBRANESR01EB001035 · NIBIB · BRANDEIS UNIVERSITY · PI HERZFELD, JUDITH · 2003 to 2012
$2.9M
NIBIB NIH HHS P41 EB002026NIBIB NIH HHS R01 EB001035NIBIB NIH HHS R01 EB001960NIBIB NIH HHS R01 EB002804NIGMS NIH HHS P41 GM132079NIGMS NIH HHS R01 GM132997
6 · The paper itself

Abstract

Despite much attention, the path of the highly consequential primary proton transfer in the light-driven ion pump bacteriorhodopsin (bR) remains mysterious. Here we use DNP-enhanced magic angle spinning (MAS) NMR to study critical elements of the active site just before the Schiff base (SB) deprotonates (in the L intermediate), immediately after the SB has deprotonated and Asp85 has become protonated (in the M

Indexed as

LightNuclear Magnetic Resonance, BiomolecularBacteriorhodopsinsHalobacterium salinarumIon PumpsBacteriorhodopsinsIon Pumps

Identifiers

PMID29489362
PMCPMC8313245
OpenAlexW2792739993

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.