Evidence map›Paper›PMID 29489335›Full record

ReviewAccounts of chemical research2018

Radiolabeling Silica-Based Nanoparticles via Coordination Chemistry: Basic Principles, Strategies, and Applications.

Dalong Ni, Dawei Jiang, Emily B Ehlerding, Peng Huang, Weibo Cai

Open access · greenAbstract readReview
In one paragraph

Review in Accounts of chemical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
10.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 93 citations in OpenAlex.

  1. Review
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  3. Review
  4. Article
  5. Review
  6. ComparativeDalton transactions (Cambridge, England : 2003) · 2025
    Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Exploring innovative strides in radiolabeled nanoparticle progress for multimodality cancer imaging and theranostic applications.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Review
  12. In Vitro Assessment ofPharmaceuticals (Basel, Switzerland) · 2024
    Article
  13. Brachytherapy at the nanoscale with protein functionalized and intrinsically radiolabeled [European journal of nuclear medicine and molecular imaging · 2024
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Nanomaterial Probes for Nuclear Imaging.Nanomaterials (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Dalong NiDepartments of Radiology, Medical Physics, Biomedical Engineering, Materials Science & Engineering, and Pharmaceutical Sciences (Drug Delivery Core) , University of Wisconsin-Madison , Madison , Wisconsin 53705 , United States.ORCID 0000-0001-6679-5414
Dawei JiangDepartments of Radiology, Medical Physics, Biomedical Engineering, Materials Science & Engineering, and Pharmaceutical Sciences (Drug Delivery Core) , University of Wisconsin-Madison , Madison , Wisconsin 53705 , United States.ORCID 0000-0002-4072-0075
Emily B EhlerdingDepartments of Radiology, Medical Physics, Biomedical Engineering, Materials Science & Engineering, and Pharmaceutical Sciences (Drug Delivery Core) , University of Wisconsin-Madison , Madison , Wisconsin 53705 , United States.
Peng HuangGuangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Laboratory of Evolutionary Theranostics, School of Biomedical Engineering, Health Science Center , Shenzhen University , Shenzhen 518060 , China.ORCID 0000-0003-3651-7813
Weibo CaiDepartments of Radiology, Medical Physics, Biomedical Engineering, Materials Science & Engineering, and Pharmaceutical Sciences (Drug Delivery Core) , University of Wisconsin-Madison , Madison , Wisconsin 53705 , United States.ORCID 0000-0003-4641-0833
University of Wisconsin–Madison · USShenzhen University · CN

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Christian Capitini · 1985 to 2026
$142.6M
U.W. RADIOLOGICAL SCIENCES TRAINING PROGRAMT32CA009206 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Bryan Patrick Bednarz · 1985 to 2026
$12.1M
Chemistry-Biology Interface Training ProgramT32GM008505 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI BLACKWELL, HELEN E. · 1993 to 2023
$9.8M
NCI NIH HHS P30 CA014520NCI NIH HHS T32 CA009206NIGMS NIH HHS T32 GM008505
6 · The paper itself

Abstract

As one of the most biocompatible and well-tolerated inorganic nanomaterials, silica-based nanoparticles (SiNPs) have received extensive attention over the last several decades. Recently, positron emission tomography (PET) imaging of radiolabeled SiNPs has provided a highly sensitive, noninvasive, and quantitative readout of the organ/tissue distribution, pharmacokinetics, and tumor targeting efficiency in vivo, which can greatly expedite the clinical translation of these promising NPs. Encouraged by the successful PET imaging of patients with metastatic melanoma using

Indexed as

AnimalsCopper RadioisotopesFluorine RadioisotopesGallium RadioisotopesHumansIodine RadioisotopesMolecular ImagingNanoparticlesNeoplasmsPositron-Emission TomographyRadioisotopesSilicon DioxideZirconiumCopper-64Copper RadioisotopesFluorine RadioisotopesGallium-68Gallium RadioisotopesIodine-124Iodine RadioisotopesRadioisotopesSilicon DioxideZirconiumZirconium-89

Identifiers

PMID29489335
PMCPMC5878690
OpenAlexW2787882323

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.