ArticleEnvironmental health perspectives2018
Maternal Plasma per- and Polyfluoroalkyl Substance Concentrations in Early Pregnancy and Maternal and Neonatal Thyroid Function in a Prospective Birth Cohort: Project Viva (USA).
Article in Environmental health perspectives, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 101 citations in OpenAlex.
- Risk Factors for Thyroid Function Test Abnormalities During Pregnancy: A Systematic Review of the Literature to Validate Current Risk Factors and Identify Novel Ones.Thyroid : official journal of the American Thyroid Association · 2025Pooled it
- Exposure to per- and polyfluoroalkyl substances (PFAS) and development of autoimmunity in humans and animals: a scoping review.Archives of toxicology · 2026Article
- A two-step Bayesian clustering approach to relate PFAS mixture profiles and dietary patterns in early pregnancy.Environmental research · 2026Article
- Differential correlations of serum PFASs with thyroid hormones in girls with central and incomplete precocious puberty: a machine learning analysis.Frontiers in molecular biosciences · 2026Article
- Prenatal Exposure to Per- and Polyfluoroalkyl Substances and Maternal Thyroid Function during Pregnancy in a Cohort with High Familial Likelihood of Autism Spectrum Disorder.Environmental science & technology · 2025Article
- Per and polyfluoroalkyl substances affect thyroid hormones for people with a history of exposure from drinking water.Scientific reports · 2025Article
- Short-chain PFAS exposure during gestation and breastfeeding alters learning and memory in adulthood: possible mechanisms related to brain development.Frontiers in toxicology · 2025Article
- A prospective cohort study of persistent endocrine-disrupting chemicals and perceived stress.American journal of epidemiology · 2024Article
- Associations of PFAS concentrations during pregnancy and midlife with bone health in midlife: Cross-sectional and prospective findings from Project Viva.Environment international · 2024Article
- Adverse outcome pathway for the neurotoxicity of Per- and polyfluoroalkyl substances: A systematic review.Eco-Environment & Health · 2024Review
- Associations between gestational exposure to perfluoroalkyl substances, fetal growth, and the mediation effect of thyroid hormones.Scientific reports · 2024Article
- Review
- Per- and polyfluoroalkyl substances (PFAS), perceived stress, and depressive symptoms in a prospective cohort study of black women.The Science of the total environment · 2024Article
- Per- and polyfluoroalkyl substances (PFAS) and thyroid hormone measurements in dried blood spots and neonatal characteristics: a pilot study.Journal of exposure science & environmental epidemiology · 2023Article
- Prenatal Exposure to Per- and Polyfluoroalkyl Substances, Maternal Thyroid Dysfunction, and Child Autism Spectrum Disorder.Endocrinology and metabolism (Seoul, Korea) · 2022Review
- Chronic exposure to perfluorohexane sulfonate leads to a reproduction deficit by suppressing hypothalamic kisspeptin expression in mice.Journal of ovarian research · 2021Article
- A pathway level analysis of PFAS exposure and risk of gestational diabetes mellitus.Environmental health : a global access science source · 2021Review
- Endocrine Disruptor Potential of Short- and Long-Chain Perfluoroalkyl Substances (PFASs)-A Synthesis of Current Knowledge with Proposal of Molecular Mechanism.International journal of molecular sciences · 2021Review
- Per- and polyfluoroalkyl substance mixtures and gestational weight gain among mothers in the Health Outcomes and Measures of the Environment study.International journal of hygiene and environmental health · 2021Article
- Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundPrenatal exposure to some per- and polyfluoroalkyl substances (PFASs) may disrupt maternal and neonatal thyroid function, which is critical for normal growth and neurodevelopment.
objectivesWe examined associations of PFAS exposure during early pregnancy with maternal and neonatal thyroid hormone levels.
methodsWe studied 732 mothers and 480 neonates in Project Viva, a longitudinal prebirth cohort in Boston, Massachusetts. We quantified six PFASs, including perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS), and maternal thyroid hormones [thyroxine (T
resultsPFAS concentrations were not associated with maternal T
conclusionsIn this study, prenatal exposure to some PFASs during early pregnancy was inversely associated with maternal FT
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.