Evidence map›Paper›PMID 29488460›Full record

ArticleThe American journal of tropical medicine and hygiene2018

A Prospective Hospital Study to Evaluate the Diagnostic Accuracy of Rapid Diagnostic Tests for the Early Detection of Leptospirosis in Laos.

Sabine Dittrich, Latsaniphone Boutthasavong, Dala Keokhamhoung, Weerawat Phuklia, Scott B Craig, Suhella M Tulsiani, Mary-Anne Burns, Steven L Weier, David A B Dance, Viengmon Davong and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Retrospective Molecular Detection and Characterization of PathogenicTropical medicine and infectious disease · 2026
    Article
  3. Laboratory Diagnosis of Leptospirosis.Methods in molecular biology (Clifton, N.J.) · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Leptospirosis infections among hospital patients, Sarawak, Malaysia.Tropical diseases, travel medicine and vaccines · 2021
    Article
  9. Article
  10. Algorithm in the Diagnosis of Febrile Illness Using Pathogen-specific Rapid Diagnostic Tests.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 4 countries.

Sabine DittrichNuffield Department of Medicine, Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom.
Latsaniphone BoutthasavongMicrobiology Laboratory, Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Mahosot Hospital, Vientiane, Lao PDR.
Dala KeokhamhoungNuffield Department of Medicine, Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom.
Weerawat PhukliaMicrobiology Laboratory, Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Mahosot Hospital, Vientiane, Lao PDR.
Scott B CraigQueensland Health Forensic and Scientific Service, WHO Collaborating Centre for Reference and Research on Leptospirosis, Brisbane, Australia.
Suhella M TulsianiSection for Global Health, Department of Public Health, Copenhagen Centre for Disaster Research, University of Copenhagen, Copenhagen, Denmark.
Mary-Anne BurnsQueensland Health Forensic and Scientific Service, WHO Collaborating Centre for Reference and Research on Leptospirosis, Brisbane, Australia.
Steven L WeierFaculty of Health, Queensland University of Technology, Brisbane, Australia.
David A B DanceFaculty of Tropical and Infectious Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Viengmon DavongMicrobiology Laboratory, Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Mahosot Hospital, Vientiane, Lao PDR.
Manivanh VongsouvathMicrobiology Laboratory, Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Mahosot Hospital, Vientiane, Lao PDR.
Mayfong MayxayFaculty of Postgraduate Studies, University of Health Sciences, Vientiane, Lao PDR.
Rattanaphone PhetsouvanhNuffield Department of Medicine, Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom.
Paul N NewtonNuffield Department of Medicine, Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom.
Kate WoodsNational Infection Service (NIS), Public Health England (PHE), London, United Kingdom.
Mahosot Hospital · LALao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit · LAQueensland Health · AUPublic Health England · GBQueensland University of Technology · AUUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leptospirosis is a globally important cause of acute febrile illness, and a common cause of non-malarial fever in Asia, Africa, and Latin America. Simple rapid diagnostic tests (RDTs) are needed to enable health-care workers, particularly in low resource settings, to diagnose leptospirosis early and give timely targeted treatment. This study compared four commercially available RDTs to detect human IgM against

Indexed as

AdolescentAdultAgedAged, 80 and overAgglutination TestsAntibodies, BacterialChildChild, PreschoolEarly DiagnosisFemaleHumansImmunoglobulin MInfantLeptospirosisMaleMiddle AgedAntibodies, BacterialImmunoglobulin M

Identifiers

PMID29488460
PMCPMC5928825
OpenAlexW2792913840

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.