Evidence map›Paper›PMID 29488210›Full record

ArticleInternational journal of cancer2018

Metabolic obesity phenotypes and risk of colorectal cancer in postmenopausal women.

Geoffrey C Kabat, Mimi Y Kim, Marcia Stefanick, Gloria Y F Ho, Dorothy S Lane, Andrew O Odegaard, Michael S Simon, Jennifer W Bea, Juhua Luo, Sylvia Wassertheil-Smoller and 1 more

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in International journal of cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 3 pooled it
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 42 citations in OpenAlex.

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  18. Metabolically Defined Body Size Phenotypes and Risk of Endometrial Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC).Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 1 country.

Geoffrey C KabatDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY.ORCID 0000-0001-8251-1389
Mimi Y KimDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY.
Marcia StefanickDepartment of Medicine, Stanford University, Stanford, CA.
Gloria Y F HoDepartment of Occupational Medicine, Epidemiology and Prevention, Northwell Health, Great Neck, NY.
Dorothy S LaneDepartment of Preventive Medicine, School of Medicine, Stony Brook University, Stony Brook, NY.
Andrew O OdegaardDepartment of Epidemiology, School of Medicine, University of California at Irvine, Irvine, CA.
Michael S SimonKarmanos Cancer Institute, Detroit, MI.ORCID 0000-0002-3237-6761
Jennifer W BeaDepartment of Medicine, Arizona Cancer Center, Tucson, AZ.
Juhua LuoDepartment of Epidemiology and Biostatistics, School of Public Health, University of Indiana, Bloomington, IN.
Sylvia Wassertheil-SmollerDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY.
Thomas E RohanDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY.
Albert Einstein College of Medicine · USArizona Oncology · USIndiana University Bloomington · USNorthwell Health · USStanford University · USStony Brook School · USThe Barbara Ann Karmanos Cancer Institute · USUniversity of California, Irvine · US

Funding

Tumor Biology and Microenvironment (Program 1)P30CA022453 · NCI · WAYNE STATE UNIVERSITY · PI PAUL M STEMMER · 1985 to 2026
$68.4M
NCI NIH HHS P30 CA022453
6 · The paper itself

Abstract

Obesity has been postulated to increase the risk of colorectal cancer by mechanisms involving insulin resistance and the metabolic syndrome. We examined the associations of body mass index (BMI), waist circumference, the metabolic syndrome, metabolic obesity phenotypes and homeostasis model-insulin resistance (HOMA-IR-a marker of insulin resistance) with risk of colorectal cancer in over 21,000 women in the Women's Health Initiative CVD Biomarkers subcohort. Women were cross-classified by BMI (18.5-<25.0, 25.0-<30.0 and ≥30.0 kg/m

Indexed as

PhenotypeAgedBiomarkersBody Mass IndexColorectal NeoplasmsFemaleFollow-Up StudiesHumansInsulin ResistanceMetabolic SyndromeMiddle AgedObesityOdds RatioPopulation SurveillancePostmenopauseRisk AssessmentBiomarkersbody mass indexcolorectal cancer riskHOMA-IRmetabolic statuspostmenopausal womenwaist circumference

Identifiers

PMID29488210
PMCPMC6876750
OpenAlexW2792944378

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.