ArticleWorld journal of surgery2018
Neoadjuvant Chemoradiotherapy for Patients with cT3/Nearly T4 Esophageal Cancer: Is Sarcopenia Correlated with Postoperative Complications and Prognosis?
Article in World journal of surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 6 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 6 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- The impact of sarcopenia on esophagectomy for cancer: a systematic review and meta-analysis.BMC surgery · 2023Pooled it
- The prognostic value of sarcopenia in oesophageal cancer: A systematic review and meta-analysis.Journal of cachexia, sarcopenia and muscle · 2023Pooled it
- Computed tomography-defined low skeletal muscle index and density in cancer patients: observations from a systematic review.Journal of cachexia, sarcopenia and muscle · 2021Pooled it
- The Impact of Preoperative Sarcopenia on Survival Prognosis in Patients Receiving Neoadjuvant Therapy for Esophageal Cancer: A Systematic Review and Meta-Analysis.Frontiers in oncology · 2021Pooled it
- Sarcopenia and Short-Term Outcomes After Esophagectomy: A Meta-analysis.Annals of surgical oncology · 2020Pooled it
- Low skeletal muscle mass and postoperative morbidity in surgical oncology: a systematic review and meta-analysis.Journal of cachexia, sarcopenia and muscle · 2020Pooled it
- Impact of Skeletal Muscle Loss and Sarcopenia on Outcomes of Locally Advanced Esophageal Cancer during Neoadjuvant Chemoradiation.Annals of surgical oncology · 2024Article
- Therapeutic strategy aiming at R0 resection for borderline-resectable esophageal squamous cell carcinoma using induction chemotherapy with docetaxel, cisplatin, and 5-fluorouracil.General thoracic and cardiovascular surgery · 2023Article
- Prognostic Value of Sarcopenia and Metabolic Parameters ofDiagnostics (Basel, Switzerland) · 2023Article
- Clinical significance of sarcopenic dysphagia for patients with esophageal cancer undergoing esophagectomy: A review.Annals of gastroenterological surgery · 2022Review
- Management of elderly patients with esophageal squamous cell cancer.Japanese journal of clinical oncology · 2022Review
- Skeletal muscle loss during neoadjuvant chemotherapy predicts poor prognosis in patients with breast cancer.BMC cancer · 2022Article
- Influence of sarcopenia, clinical data, and 2-[European journal of nuclear medicine and molecular imaging · 2022Article
- Comparison of Inflammation-Based Prognostic Scores Associated with the Prognostic Impact of Adenocarcinoma of Esophagogastric Junction and Upper Gastric Cancer.Annals of surgical oncology · 2021Article
- Prognostic significance of nutritional markers in metastatic gastric and esophageal adenocarcinoma.Cancer medicine · 2021Article
- The Influence of Pretherapeutic and Preoperative Sarcopenia on Short-Term Outcome after Esophagectomy.Cancers · 2020Article
- Skeletal muscle loss during systemic chemotherapy for colorectal cancer indicates treatment response: a pooled analysis of a multicenter clinical trial (KSCC 1605-A).International journal of clinical oncology · 2019Article
- Prognostic value of paravertebral muscle density in patients with spinal metastases from gastrointestinal cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019Article
Corrections and comments
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Authors and funding
15 authors at 1 institution in 1 country.
Funding
Abstract
backgroundSince the clinical impact of sarcopenia on multimodal therapy for patients with esophageal cancer is not well understood, this study was conducted to determine the influence of sarcopenia on the efficacy of neoadjuvant chemoradiotherapy (NACRT) for locally advanced esophageal cancer.
methodsThe skeletal muscle index was quantified at the level of the third lumbar vertebra on computed tomography images, and sarcopenia was defined as a skeletal muscle index that was less than the average for each gender. We compared treatment outcomes in patients with cT3 and nearly T4 thoracic esophageal squamous cell carcinoma between the sarcopenia group (n = 85) and the non-sarcopenia group (n = 72).
resultsThe 5-year survival rates were 33.4% in the non-sarcopenia group and 31.5% in the sarcopenia group; these differences were not significant. The prognosis of the patients with sarcopenia was worse than that of the patients without sarcopenia in the surgery-alone group, but there was no difference between patients with and without sarcopenia in the NACRT group.
conclusionsNACRT could be a useful option for patients with locally advanced esophageal squamous cell carcinoma, even for those with sarcopenia, without increasing the incidence of morbidity and mortality.
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Registered trials
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