ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2018
Network analysis of drug-related problems in hospitalized patients with hematologic malignancies.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- Determination of drug-related problems in the hematology service: a prospective interventional study.BMC cancer · 2024Article
- Consultation-Based Deprescribing Service to Optimize Palliative Care for Terminal Cancer Patients.Journal of clinical medicine · 2023Article
- A Network Analysis of Drug Combinations Associated with Acute Generalized Exanthematous Pustulosis (AGEP).Journal of clinical medicine · 2021Article
- Nationwide prevalence of potential drug-drug interactions associated with non-anticancer agents in patients on oral anticancer agents in South Korea.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Article
- Article
- Identification and Resolution of Drug-Related Problems among Childhood Cancer Patients in Ethiopia.Journal of oncology · 2020Article
- A chronological pharmacovigilance network analytics approach for predicting adverse drug events.Journal of the American Medical Informatics Association : JAMIA · 2018Article
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 1 country.
Funding
Abstract
purposeNetwork analysis was conducted to systematically analyze the relationship between causative drugs and types of drug-related problems (DRPs) in hospitalized patients with hematologic malignancies.
methodsA total of 1187 DRPs identified in hematology wards between 2013 and 2015 were analyzed. DRPs were classified into 11 sub-domains for problems and 35 sub-domains for causes according to Pharmaceutical Care Network Europe classification. Causative drugs were classified by Anatomical Therapeutic Chemical code. Network analytic tool was used to represent the relationship between drugs, causes, and problems. In-degree centrality (C
resultsThe following drugs accounted for more than 5% of DRP, including antibacterials (J01, 26.5%), drugs for acid-related disorders (A02, 11.5%), antiemetics (A04, 9.7%), antifungals (J02, 8.8%), and antineoplastic agents (L01, 7.0%). Inappropriate combinations (C1.3, C
conclusionsDRPs were mainly related to medications for supportive care. More attention should be paid to interactions of drugs used for acid-related disorders, dose adjustment of antibacterials, and omission of antiemetics in hospitalized patients with hematologic malignancy.
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