Trial reportEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2018
Olfactory cleft evaluation: a predictor for olfactory function in smell-impaired patients?
Trial report in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The trial behind it
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Who cites it
14 citing papers in PubMed, 20 citations in OpenAlex.
- Reversible obstruction of the olfactory cleft: impact on olfactory perception and nasal patency.International forum of allergy & rhinology · 2020Trial
- The Unmet Need of Olfactory Testing in Inflammatory Disorders of the Upper Airways-An EAACI Position Paper.Allergy · 2026Review
- Implications of Intranasal Trigeminal Nerve Function on the Surgical Management of Nasal Obstruction.ORL; journal for oto-rhino-laryngology and its related specialties · 2025Review
- Clinical and Imaging Evaluation of COVID-19-Related Olfactory Dysfunction.American journal of rhinology & allergy · 2023Article
- [Application research and development of objective examination of olfactory function].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2022Article
- Transient modifications of the olfactory bulb on MR follow-up of COVID-19 patients with related olfactory dysfunction.Journal of neuroradiology = Journal de neuroradiologie · 2022Article
- [Olfactory and gustatory disorders].HNO · 2022Article
- Naphthalene: irritative and inflammatory effects on the airways.International archives of occupational and environmental health · 2021Article
- The Olfactory Cleft Endoscopy Scale: a multi-institutional validation study in chronic rhinosinusitis.Rhinology · 2021Article
- Radiological Markers of the Olfactory Cleft: Relations to Unilateral Orthonasal and Retronasal Olfactory Function.Diagnostics (Basel, Switzerland) · 2020Article
- Clinical and Radiological Evaluations of COVID-19 Patients With Anosmia: Preliminary Report.The Laryngoscope · 2020Article
- Temporary olfactory improvement in chronic rhinosinusitis with nasal polyps after treatment.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2018Review
- Diagnosis of Anosmia and Hyposmia: A Systematic Review.Allergy & rhinology (Providence, R.I.)Review
- The outcome of fluticasone nasal spray on anosmia and triamcinolone oral paste in taste dysgeusia in COVID-19 patients.American journal of otolaryngologyArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
objectiveIn this study, we introduce an extension of previous work by Soler et al. (Int Forum Allergy Rhinol 6(3):293-298, 2016) on a modified endoscopic scoring system of the Lund-Kennedy Score (focusing on the olfactory cleft) to evaluate its correlation with the olfactory function in patients with various smell disorders. STUDY
designA prospective cohort study.
methodsTwo-hundred and eighty-eight participants were included and categorized in five groups according to the cause of their olfactory disorder: (0) control, (1) idiopathic, (2) sino-nasal, (3) postinfectious and (4) post traumatic olfactory loss. Olfaction was evaluated using the "Sniffin' Sticks" test. The classical Lund-Kennedy scoring and a new olfactory cleft specific Lund-Kennedy scoring (OC-LK) were performed to evaluate mucosal changes.
resultsSignificantly higher OC-LK scores on both sides were found in smell-impaired patients as compared to normosmic controls. When comparing the 4 groups, a significant difference of the OC-LK score were present between the sino-nasal and all other groups. Most importantly, significant negative correlations with strong effects were shown in the sino-nasal group between the OC-LK score and odor discrimination and odor identification. However, no such correlation emerged between the classical LK score and smell function.
conclusionOlfactory cleft evaluation using the OC-LK score correlates with the olfactory function in patients with sino-nasal smell disorder. This diagnostic tool may reflect the underlying pathophysiological mechanism of sino-nasal smell loss, and therefore, should complement olfactory diagnostics in patients with sino-nasal smell disorder.
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