Evidence map›Paper›PMID 29487992›Full record

ArticlePediatric surgery international2018

Outcomes and complications of surgery in patients with intermediate-risk neuroblastoma: experience from an Indian tertiary Cancer Centre.

Sajid S Qureshi, Monica Bhagat, Caleb Harris, Girish Chinnaswamy, Tushar Vora, Seema Kembhavi, Maya Prasad, Mukta Ramadwar, Omshree Shetty, Siddharth Laskar and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in Pediatric surgery international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sajid S QureshiDivision of Pediatric Surgical Oncology, Department of Surgical Oncology, Tata Memorial Centre, Ernest Borges Road, Parel, Bombay, 400012, India. sajidshafiques@hotmail.com.
Monica BhagatDivision of Pediatric Surgical Oncology, Department of Surgical Oncology, Tata Memorial Centre, Ernest Borges Road, Parel, Bombay, 400012, India.
Caleb HarrisDivision of Pediatric Surgical Oncology, Department of Surgical Oncology, Tata Memorial Centre, Ernest Borges Road, Parel, Bombay, 400012, India.
Girish ChinnaswamyDivision of Pediatric Oncology, Department of Medical Oncology, Tata Memorial Centre, Bombay, India.
Tushar VoraDivision of Pediatric Oncology, Department of Medical Oncology, Tata Memorial Centre, Bombay, India.
Seema KembhaviDepartment of Radiology, Tata Memorial Centre, Bombay, India.
Maya PrasadDivision of Pediatric Oncology, Department of Medical Oncology, Tata Memorial Centre, Bombay, India.
Mukta RamadwarDepartment of Pathology and Molecular Genetics, Tata Memorial Centre, Bombay, India.
Omshree ShettyDepartment of Pathology and Molecular Genetics, Tata Memorial Centre, Bombay, India.
Siddharth LaskarDepartment of Radiation Oncology, Tata Memorial Centre, Bombay, India.
Nehal KhannaDepartment of Radiation Oncology, Tata Memorial Centre, Bombay, India.
Nayna AminDepartment of Anaesthesia, Tata Memorial Centre, Bombay, India.
Sanjay TaloleDepartment of Biostatistics, Tata Memorial Centre, Bombay, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe treatment of intermediate risk (IR) neuroblastoma has evolved with the focus now on reducing the drugs, dosage, and duration of chemotherapy. The aim of this study is to present the outcomes of treatment and the complications of surgery in patients with IR neuroblastoma treated at a tertiary cancer center in India.

methodsAll eligible patients with IR neuroblastoma treated between April 2005 and August 2016 were identified. The presence and number of image-defined risk factors (IDRF) before and after neoadjuvant chemotherapy were retrospectively analyzed as were the extent of surgery, complications, and outcomes.

resultsOf 282 neuroblastoma patients treated during the study period, 54 had IR neuroblastoma. Complete excision was achieved in 25 patients. There were 26 surgical complications in 22 patients with a similar incidence in patients with complete (n = 13) or incomplete (n = 13) resection (p = 0.78). After a median follow-up of 47 months, the 4-year overall and event-free survival was 91.5% and 75%, respectively. There was no difference in survival between patients who underwent complete resection versus those with incomplete resection (p = 0.9).

conclusionOutcomes of IR neuroblastoma are favorable. The extent of resection does not affect the survival and complications can occur even when the resection is incomplete.

Indexed as

Neoplasm StagingTertiary Care CentersChildChild, PreschoolDisease-Free SurvivalFemaleHumansImage-Guided BiopsyIncidenceIndiaInfantInfant, NewbornMagnetic Resonance ImagingMaleNeuroblastomaPositron-Emission TomographyComplete resectionComplicationsImage-defined risk factorsIncomplete resectionIntermediate riskNeuroblastomaOutcomesSurgery

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.