Evidence map›Paper›PMID 29487881›Full record

ArticleJournal of medical imaging (Bellingham, Wash.)2018

Preoperative measurement of cutaneous melanoma and nevi thickness with photoacoustic imaging.

Aedán Breathnach, Elizabeth Concannon, Jemima J Dorairaj, Shazrinizam Shaharan, James McGrath, Jithin Jose, Jack L Kelly, Martin J Leahy

Abstract read
In one paragraph

Article in Journal of medical imaging (Bellingham, Wash.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Assessment of Breast Tumors Using Multispectral Optoacoustic Tomography in a Surgical Setting.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Trial
  4. Non-invasive Imaging Modalities for Breslow Thickness Estimation in Melanoma: A Scoping Review.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2026
    Review
  5. Article
  6. Review
  7. Non-invasive characterization of melanoma depth at single-cell resolution.Journal of the European Academy of Dermatology and Venereology : JEADV · 2025
    Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Photoacoustic imaging of periorbital skin cancerBiomedical optics express · 2022
    Article
  17. Review
  18. Article
  19. Regional motion correction forBiomedical optics express · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Aedán BreathnachNational University of Ireland (NUI), Tissue Optics and Microcirculation Imaging Facility, National Biophotonics and Imaging Platform, Galway, Ireland.
Elizabeth ConcannonUniversity Hospital Galway, University College Hospital Galway, Department of Plastic and Reconstructive Surgery, Ireland.
Jemima J DorairajUniversity Hospital Galway, University College Hospital Galway, Department of Plastic and Reconstructive Surgery, Ireland.ORCID https://orcid.org/0000-0002-6830-3417
Shazrinizam ShaharanUniversity Hospital Galway, University College Hospital Galway, Department of Plastic and Reconstructive Surgery, Ireland.
James McGrathNational University of Ireland (NUI), Tissue Optics and Microcirculation Imaging Facility, National Biophotonics and Imaging Platform, Galway, Ireland.
Jithin JoseFUJIFILM Visualsonics Inc., Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0002-8389-5596
Jack L KellyUniversity Hospital Galway, University College Hospital Galway, Department of Plastic and Reconstructive Surgery, Ireland.
Martin J LeahyNational University of Ireland (NUI), Tissue Optics and Microcirculation Imaging Facility, National Biophotonics and Imaging Platform, Galway, Ireland.ORCID https://orcid.org/0000-0003-1558-4574

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photoacoustic imaging (PAI) is an emerging biomedical imaging technology, which can potentially be used in the clinic to preoperatively measure melanoma thickness and guide biopsy depth and sample location. We recruited 27 patients with pigmented cutaneous lesions suspicious for melanoma to test the feasibility of a handheld linear-array photoacoustic probe in imaging lesion architecture and measuring tumor depth. The probe was assessed in terms of measurement accuracy, image quality, and ease of application. Photoacoustic scans included single wavelength, spectral unmixing, and three-dimensional (3-D) scans. The photoacoustically measured lesion thickness gave a high correlation with the histological thickness measured from resected surgical samples ([Formula: see text], [Formula: see text] for melanomas, [Formula: see text], [Formula: see text] for nevi). Thickness measurements were possible for 23 of 26 cases for nevi and all (6) cases for melanoma. Our results show that handheld, linear-array PAI is highly reliable in measuring cutaneous lesion thickness

Indexed as

biopsyBreslow depthhistologyspectral unmixingstaging

Identifiers

PMID29487881
PMCPMC5809700

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.