Evidence map›Paper›PMID 29487874›Full record

ArticleBioMed research international2018

Epidemiological Profile and Risk Factors for Acquiring HBV and/or HCV in HIV-Infected Population Groups in Nepal.

Manjula Bhattarai, Jagat Bahadur Baniya, Nirmal Aryal, Bimal Shrestha, Ramanuj Rauniyar, Anurag Adhikari, Pratik Koirala, Pardip Kumar Oli, Ram Deo Pandit, David A Stein and 1 more

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Manjula BhattaraiKathmandu Research Institute for Biological Sciences, Lalitpur, Nepal.
Jagat Bahadur BaniyaNational Public Health Laboratory, Teku, Kathmandu, Nepal.
Nirmal AryalVirology Units, Central Department of Biotechnology, Tribhuvan University, Kirtipur, Kathmandu, Nepal.
Bimal ShresthaNational Public Health Laboratory, Teku, Kathmandu, Nepal.
Ramanuj RauniyarKathmandu Research Institute for Biological Sciences, Lalitpur, Nepal.
Anurag AdhikariKathmandu Research Institute for Biological Sciences, Lalitpur, Nepal.ORCID 0000-0003-3168-0558
Pratik KoiralaKathmandu Research Institute for Biological Sciences, Lalitpur, Nepal.ORCID 0000-0003-1946-7623
Pardip Kumar OliSagarmatha Diagnostic Centre, Nepalgunj, Banke, Nepal.
Ram Deo PanditAyurveda Campus, TU, Kirtipur, Kathmandu, Nepal.
David A SteinDepartment of Biomedical Sciences, Oregon State University, Corvallis, OR, USA.
Birendra Prasad GuptaVirology Units, Central Department of Biotechnology, Tribhuvan University, Kirtipur, Kathmandu, Nepal.ORCID 0000-0001-6477-6260
National Public Health Laboratory · NPTribhuvan University · NPOregon State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

HBV and HCV infections are widespread among the HIV-infected individuals in Nepal. The goals of this study were to investigate the epidemiological profile and risk factors for acquiring HBV and/or HCV coinfection in disadvantaged HIV-positive population groups in Nepal. We conducted a retrospective study on blood samples from HIV-positive patients from the National Public Health Laboratory at Kathmandu to assay for HBsAg, HBeAg, and anti-HCV antibodies, HIV viral load, and CD4+ T cell count. Among 579 subjects, the prevalence of HIV-HBV, HIV-HCV, and HIV-HBV-HCV coinfections was 3.62%, 2.93%, and 0.34%, respectively. Multivariate regression analysis indicated that spouses of HIV-positive migrant labourers were at significant risk for coinfection with HBV infection, and an age of >40 years in HIV-infected individuals was identified as a significant risk factor for HCV coinfection. Overall our study indicates that disadvantaged population groups such as intravenous drug users, migrant workers and their spouses, female sex workers, and men who have sex with HIV-infected men are at a high and persistent risk of acquiring viral hepatitis. We conclude that Nepalese HIV patients should receive HBV and HCV diagnostic screening on a regular basis.

Indexed as

AdultCD4-Positive T-LymphocytesCoinfectionFemaleHepacivirusHepatitis BHepatitis B e AntigensHepatitis B Surface AntigensHepatitis B virusHepatitis CHepatitis C AntibodiesHIV InfectionsHumansMaleMiddle AgedNepalHepatitis B e AntigensHepatitis B Surface AntigensHepatitis C Antibodies

Identifiers

PMID29487874
PMCPMC5816881
OpenAlexW2782536716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.