ArticleBioMed research international2018
Ultrasound in Prenatal Diagnostics and Its Impact on the Epidemiology of Spina Bifida in a National Cohort from Denmark with a Comparison to Sweden.
Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Diagnostic accuracy of ultrasound screening for fetal structural abnormalities during the first and second trimester of pregnancy in low-risk and unselected populations.The Cochrane database of systematic reviews · 2024Pooled it
- Factors influencing harmonized health data collection, sharing and linkage in Denmark and Switzerland: A systematic review.PloS one · 2019Pooled it
- Prenatal detection of major congenital malformations in a cohort of 19 367 Danish fetuses with a complete follow-up six months after birth.Acta obstetricia et gynecologica Scandinavica · 2023Article
- Genetics in prenatal diagnosis.Singapore medical journal · 2023Review
- Pressure injuries are common in children with myelomeningocele: Results from a follow-up programme and register.Acta paediatrica (Oslo, Norway : 1992) · 2022Article
- Perspectives on urological care in spina bifida patients.Intractable & rare diseases research · 2021Review
- Views on everyday life among adults with spina bifida: an exploration through photovoice.International journal of qualitative studies on health and well-being · 2020Article
- Spina bifida and pediatric cancers.Pediatric hematology and oncology · 2020Article
- Adults with spina bifida: A cross-sectional study of health issues and living conditions.Brain and behavior · 2020Article
- Pain and health status in adults with myelomeningocele living in Sweden.Journal of pediatric rehabilitation medicine · 2018Article
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of this study was to assess the incidence, the prenatal detection rate by ultrasound, and the pregnancy outcome of spina bifida (SB) in Denmark (DK) in 2008-2015 and to compare results to national data from Sweden.
methodsData were retrieved from the Danish Fetal Medicine Database, which includes International Classification of Diseases- (ICD-) 10 codes for pre- or postnatally diagnoses and pregnancy outcome. Missing data were obtained from the National Patient Register. Livebirth data with myelomeningocele (MMC) in Sweden were obtained from different databases.
resultsThere were 234 cases with SB in DK in 2008-2015. The incidence of SB was 4.9 : 10,000; 89% were detected with ultrasound prior to week 22; 90% of these pregnancies were terminated (ToP); 91% were isolated malformations of which 11% showed abnormal karyotype. The incidence of newborns with MMC was 1.3 : 10,000 in Sweden.
conclusionsUltrasound screening has a major impact on the epidemiology of SB. The prenatal detection rate of SB was high, and most SB cases were isolated and had a normal karyotype. Among women with a prenatal fetal diagnosis of SB, 90% chose to have ToP. The incidence of newborns with SB was higher in Sweden than in DK.
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