ArticleInternational journal of ophthalmology2018
Comparison of peripapillary retinal nerve fiber layer thickness between myopia severity groups and controls.
Article in International journal of ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Decreasing Radial Peripapillary Capillary Perfusion Density Correlated With Visual Field Impairment in High Myopia.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Article
- Sector-Specific Patterns of RNFL and Ganglion Cell Complex Thinning Across the Myopia Spectrum: A Cross-Sectional OCTA Study.Medicina (Kaunas, Lithuania) · 2026Article
- Differences in Retinal Thickness and Vessel Density of the Macula and Optic Disc Across Myopic Children and Adolescents.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- The neural signature of high myopia: structural and functional brain alterations and their cognitive-emotional associations.Frontiers in cell and developmental biology · 2025Review
- Heterogenous thinning of peripapillary tissues occurs early during high myopia development in juvenile tree shrews.Experimental eye research · 2024Article
- Update on the Utility of Optical Coherence Tomography in the Analysis of the Optic Nerve Head in Highly Myopic Eyes with and without Glaucoma.Journal of clinical medicine · 2023Review
- Differences in structural parameters in patients with open-angle glaucoma, high myopia and both diseases concurrently. A pilot study.PloS one · 2023Article
- Ultra-Widefield Swept-Source Optical Coherence Tomography Angiography in the Assessment of Choroidal Changes in Young Adults With Myopia.Translational vision science & technology · 2022Article
- OCT Results in Myopia: Diagnostic Difficulties in Clinical Practice?Journal of clinical medicine · 2022Article
- Article
- Nomogram of peripapillary retinal nerve fiber layer thickness in myopic eyes of north Indian population.Indian journal of ophthalmology · 2022Article
- Association of high myopia with peripapillary retinal nerve fiber layer in patients with hypertension.PloS one · 2021Article
- Distribution of IOP and its relationship with refractive error and other factors: the Anyang University Students Eye Study.International journal of ophthalmology · 2021Article
- Correlation of axial length and peripapillary retinal nerve fiber layer thickness measured by Cirrus HD optical coherence tomography in myopes.Indian journal of ophthalmology · 2020Article
- Diffusion Tensor Imaging Detects Microstructural Differences of Visual Pathway in Patients With Primary Open-Angle Glaucoma and Ocular Hypertension.Frontiers in human neuroscience · 2018Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo compare the peripapillary retinal nerve fiber layer (RNFL) thickness measured
methodsThis was a prospective cross-sectional study. All subjects underwent a full ophthalmic examination, refraction, visual field analysis and A-scan biometry. Myopic patients were classified as low myopia (LM) [spherical equivalent (SE) from greater than -0.5 D, up to -3.0 D], moderate myopia (MM; SE greater than -3.0 D, up to -6.0 D) and high myopia (HM; SE greater than -6.0 D). The control group consisted of emmetropic (EM) patients (SE from +0.5 D to -0.5 D). A Zeiss Cirrus HD-OCT machine was used to measure the peripapillary RNFL thickness of both eyes of each subject. The mean peripapillary RNFL thickness between groups was compared using both analysis of variance and analysis of covariance.
resultsA total of 403 eyes of 403 subjects were included in this study. The mean age was 31.48±10.23y. There were 180 (44.7%) eyes with EM, 124 (30.8%) with LM, 73 (18.1%) with MM and 26 (6.5%) with HM. All groups of myopia severity had a thinner average RNFL than the EM group, but after controlling for gender, age, and axial eye length, only the HM group differed significantly from the EM group (
conclusionThe average and inferior quadrant RNFL is thinner in highly myopic eyes compared to emmetropic eyes. Refractive status must be taken into consideration when interpreting the OCT of myopic patients, as RNFL thickness varies with the degree of myopia.
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