Evidence map›Paper›PMID 29487762›Full record

ArticleWorld journal of gastrointestinal pathophysiology2018

Emergency resection surgery for colorectal cancer: Patterns of recurrent disease and survival.

Joe Littlechild, Muneer Junejo, Anne-Marie Simons, Finlay Curran, Darren Subar

Abstract read
In one paragraph

Article in World journal of gastrointestinal pathophysiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joe LittlechildDepartment of Surgery, Manchester Royal Infirmary, Manchester M13 9WL, United Kingdom.
Muneer JunejoDepartment of Surgery, Manchester Royal Infirmary, Manchester M13 9WL, United Kingdom.
Anne-Marie SimonsDepartment of Surgery, Manchester Royal Infirmary, Manchester M13 9WL, United Kingdom.
Finlay CurranDepartment of Surgery, Manchester Royal Infirmary, Manchester M13 9WL, United Kingdom.
Darren SubarHepatobiliary Surgery Unit, Royal Blackburn Hospital, Blackburn BB2 3HH, United Kingdom. darren.subar@elht.nhs.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate prognostic pathological factors associated with early metachronous disease and adverse long-term survival in these patients.

methodsClinical and histological features were analysed retrospectively over an eight-year period for prognostic impact on recurrent disease and overall survival in patients undergoing curative resection of a primary colorectal cancer.

resultsA total of 266 patients underwent curative surgery during the study period. The median age of the study cohort was 68 year (range 26 to 91) with a follow-up of 7.9 years (range 4.6 to 12.6). Resection was undertaken electively in 225 (84.6%) patients and emergency resection in 35 (13.2%). Data on timing of surgery was missing in 6 patients. Recurrence was noted in 67 (25.2%) during the study period and was predominantly early within 3 years (82.1%) and involved hepatic metastasis in 73.1%. Emergency resection (OR = 3.60,

conclusionEmergency surgery is associated with adverse disease free and long-term survival. T4 disease, LVI and LNR provide strong independent predictive value of long-term outcome and can inform surveillance strategies to improve outcomes.

Indexed as

Colorectal cancerEmergency resectionLymph node ratioMetachronous diseaseSurvival

Identifiers

PMID29487762
PMCPMC5823701

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.