Evidence map›Paper›PMID 29487664›Full record

ArticleRadiology case reports2018

Progression of tumefactive demyelinating lesion in a child demonstrated with MRI.

Marta De Simone, Barbara Brogna, Daniele Litterio Spitaleri, Giulio Cicarelli, Roberta Fantozzi, Bruno Guida

Abstract readCase Reports
In one paragraph

Article in Radiology case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marta De SimoneNeuroradiology Unit "San Giuseppe Moscati" Hospital Avellino, Amoretta Street, 83100, Avellino, Italy.
Barbara BrognaDepartment of Internal and Experimental Medicine "Magrassi-Lanzara", Institute of Radiology, Second University of Naples, Naples, Italy.
Daniele Litterio SpitaleriNeurology Unit "San Giuseppe Moscati", Hospital Avellino, Avellino, Italy.
Giulio CicarelliNeurology Unit "San Giuseppe Moscati", Hospital Avellino, Avellino, Italy.
Roberta FantozziNeurology Unit Mediterranean Neurological Institute "Neuromed", Pozzilli (IS), Italy.
Bruno GuidaNeuroradiology Unit "San Giuseppe Moscati" Hospital Avellino, Amoretta Street, 83100, Avellino, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumefactive demyelinating lesions (TDLs) are atypical presentations of various demyelinating diseases. They can mimic brain tumors in their clinical and radiological features and usually respond favorably to corticosteroid therapy. We report a case of a 17-year-old girl with a single TDL suddenly increasing in size even under steroid therapy. She underwent very strict follow-up examinations with conventional magnetic resonance and diffusion-weighted imaging, perfusion-weighted imaging, proton-magnetic resonance spectroscopy. The behavior of the lesion during the different follow-up sessions posed a diagnostic challenge as it expanded its size during the final examination, in stark contrast to what we forecast. Diagnosis of TDL was initially hypothesized, but the aggressive behavior of the lesion required biopsy.

Indexed as

Brain tumorMR diffusionMR imaging perfusionMR imaging spectroscopyTumefactive demyelinating lesion

Identifiers

PMID29487664
PMCPMC5826469

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.