Evidence map›Paper›PMID 29487617›Full record

ArticleFrontiers in genetics2018

The Druggable Pocketome of

Syed S Hassan, Syed B Jamal, Leandro G Radusky, Sandeep Tiwari, Asad Ullah, Javed Ali, Behramand, Paulo V S D de Carvalho, Rida Shams, Sabir Khan and 8 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Druggable proteins ofFrontiers in pharmacology · 2025
    Article
  2. Article
  3. Article
  4. Review
  5. Reverse vaccinology and subtractive genomics approaches for identifying common therapeutics againstThe journal of venomous animals and toxins including tropical diseases · 2021
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 9 institutions in 6 countries.

Syed S HassanDepartment of Chemistry, Islamia College University Peshawar, Peshawar, Pakistan.
Syed B JamalPG Program in Bioinformatics, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Leandro G RaduskyDepartamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina.
Sandeep TiwariPG Program in Bioinformatics, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Asad UllahDepartment of Chemistry, Islamia College University Peshawar, Peshawar, Pakistan.
Javed AliDepartment of Chemistry, Kohat University of Science and Technology, Kohat, Pakistan.
BehramandDepartment of Chemistry, Islamia College University Peshawar, Peshawar, Pakistan.
Paulo V S D de CarvalhoPG Program in Bioinformatics, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Rida ShamsDepartment of Chemistry, Islamia College University Peshawar, Peshawar, Pakistan.
Sabir KhanDepartment of Analytical Chemistry, Institute of Chemistry, São Paulo State University, São Paulo, Brazil.
Henrique C P FigueiredoAQUACEN, National Reference Laboratory for Aquatic Animal Diseases, Ministry of Fisheries and Aquaculture, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Debmalya BarhPG Program in Bioinformatics, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Preetam GhoshDepartment of Computer Science, Virginia Commonwealth University, Richmond, VA, United States.
Artur SilvaInstitute of Biological Sciences, Federal University of Pará, Belém, Brazil.
Jan BaumbachDepartment of Mathematics and Computer Science, University of Southern Denmark, Odense, Denmark.
Richard RöttgerDepartment of Mathematics and Computer Science, University of Southern Denmark, Odense, Denmark.
Adrián G TurjanskiDepartamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina.
Vasco A C AzevedoPG Program in Bioinformatics, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Universidade Federal de Minas Gerais · BRIslamia College University · PKUniversity of Southern Denmark · DKFundación Ciencias Exactas y Naturales · ARKohat University of Science and Technology · PKUniversidade Estadual Paulista (Unesp) · BRUniversidade Federal do Pará · BRUniversity of Buenos Aires · ARVirginia Commonwealth University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diphtheria is an acute and highly infectious disease, previously regarded as endemic in nature but vaccine-preventable, is caused by

Indexed as

Corynebacterium diphtheriadruggable genomeglobal druggable (GD)highly druggable (HD)pocketomeputative therapeutic targetsstructural proteomics

Identifiers

PMID29487617
PMCPMC5816920
OpenAlexW2791770377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.