Evidence map›Paper›PMID 29487599›Full record

ReviewFrontiers in immunology2018

Dectin-1-Syk-CARD9 Signaling Pathway in TB Immunity.

Matthew Wagener, J Claire Hoving, Hlumani Ndlovu, Mohlopheni J Marakalala

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. T cell-intrinsic PRR signaling in immunity and pathology.Acta biochimica et biophysica Sinica · 2026
    Review
  6. Article
  7. Review
  8. Article
  9. Intracranial infections ofFrontiers in immunology · 2025
    Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Dectin-1-Independent Macrophage Phagocytosis ofInternational journal of molecular sciences · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. CARD9 Signaling, Inflammation, and Diseases.Frontiers in immunology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Matthew WagenerDivision of Immunology, Department of Pathology, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
J Claire HovingDivision of Immunology, Department of Pathology, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
Hlumani NdlovuDepartment of Integrative Biomedical Sciences, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Mohlopheni J MarakalalaDivision of Immunology, Department of Pathology, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
University of Cape Town · ZA

Funding

Wellcome Trust 206751/Z/17/ZWellcome Trust 209293/Z/17/Z
6 · The paper itself

Abstract

One of the first steps toward mounting an effective immune response to

Indexed as

Immunity, InnateBacterial ProteinsCARD Signaling Adaptor ProteinsDectin-1Host Microbial InteractionsHumansLectins, C-TypeMycobacterium tuberculosisReceptors, Pattern RecognitionSignal TransductionSyk KinaseTuberculosisBacterial ProteinsCARD9 protein, humanCARD Signaling Adaptor ProteinsCLEC7A protein, humanDectin-1Lectins, C-TypeReceptors, Pattern RecognitionSyk KinaseSYK protein, humanC-type lectin receptorsdectin-1innate immunityMycobacterium tuberculosispathogen-associated molecular patternspattern-recognition receptorsTB immunitytuberculosis

Identifiers

PMID29487599
PMCPMC5816931
OpenAlexW2793680980

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.