Evidence map›Paper›PMID 29487527›Full record

ArticleFrontiers in pharmacology2018

RhoA/ROCK Signaling Pathway Mediates Shuanghuanglian Injection-Induced Pseudo-allergic Reactions.

Jiayin Han, Yong Zhao, Yushi Zhang, Chunying Li, Yan Yi, Chen Pan, Jingzhuo Tian, Yifei Yang, Hongyu Cui, Lianmei Wang and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. The Anaphylactic and Anti-allergenic Properties of Shuanghuanglian: A Review.Combinatorial chemistry & high throughput screening · 2026
    Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Fasudil prevents liver fibrosisWorld journal of gastroenterology · 2021
    Article
  14. Article
  15. Shuxuening injection, derived fromPharmaceutical biology · 2020
    Article
  16. Review
  17. Lonicerae japonicae flos and Lonicerae flos: a systematic review of ethnopharmacology, phytochemistry and pharmacology.Phytochemistry reviews : proceedings of the Phytochemical Society of Europe · 2020
    Review
  18. Article
  19. Article
  20. Normative Application of Xiyanping Injection: A Systematic Review of Adverse Case Reports.Evidence-based complementary and alternative medicine : eCAM · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Jiayin HanInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Yong ZhaoInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Yushi ZhangInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Chunying LiInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Yan YiInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Chen PanInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Jingzhuo TianInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Yifei YangInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Hongyu CuiInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Lianmei WangInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Suyan LiuInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Jing LiuInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Nuo DengInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Aihua LiangInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

endothelial permeabilitypseudo-allergic reactionsRhoA/ROCK signaling pathwayShuanghuanglian injectionvascular leakage

Identifiers

PMID29487527
PMCPMC5816575
OpenAlexW2809575959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.