Evidence map›Paper›PMID 29487234›Full record

ArticlemBio2018

Calcium-Dependent Protein Kinase 5 Is Required for Release of Egress-Specific Organelles in

Sabrina Absalon, Karin Blomqvist, Rachel M Rudlaff, Travis J DeLano, Michael P Pollastri, Jeffrey D Dvorin

Open access · goldAbstract read
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 77 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Physiology of invasiveFrontiers in cellular and infection microbiology · 2026
    Review
  5. Frontiers in parasitology · 2026
    Article
  6. The N-terminal region of malaria vaccine candidatebioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Characterization of the malaria parasiteMicrobiology spectrum · 2025
    Article
  9. ThemSphere · 2025
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Atlas ofeLife · 2023
    Article
  18. Article
  19. Atlas ofbioRxiv : the preprint server for biology · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Sabrina AbsalonDivision of Infectious Diseases, Boston Children's Hospital, Boston, Massachusetts, USA.
Karin Blomqvist *Division of Infectious Diseases, Boston Children's Hospital, Boston, Massachusetts, USA.
Rachel M Rudlaff *Division of Infectious Diseases, Boston Children's Hospital, Boston, Massachusetts, USA.
Travis J DeLanoDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, USA.
Michael P PollastriDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, USA.
Jeffrey D DvorinDivision of Infectious Diseases, Boston Children's Hospital, Boston, Massachusetts, USA Jeffrey.Dvorin@childrens.harvard.edu.
Harvard University · USNortheastern University · USBoston Children's Hospital · US

Funding

Repurposing human kinase inhibitor chemotypes for Neglected Tropical DiseasesR01AI114685 · NIAID · NORTHEASTERN UNIVERSITY · PI FERRINS, LORI · 2015 to 2025
$4.6M
Essential gene discovery in the malaria parasite Plasmodium falciparumDP2AI112219 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI DVORIN, JEFFREY D · 2013 to 2013
$2.6M
Molecular characterization and substrate identification of malaria kinase PfCDPK5R01AI102907 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI DVORIN, JEFFREY D · 2014 to 2017
$1.8M
NIAID NIH HHS DP2 AI112219NIAID NIH HHS R01 AI102907NIAID NIH HHS R01 AI114685
6 · The paper itself

Abstract

The human malaria parasite

Indexed as

Organelle BiogenesisCalcium-Binding ProteinsErythrocytesGene Knockdown TechniquesHost-Parasite InteractionsPlasmodium falciparumProtein KinasesProtozoan ProteinsCalcium-Binding ProteinsCDPK5 protein, Plasmodium falciparumPKB protein, Plasmodium falciparumProtein KinasesProtozoan Proteinscalcium-dependent protein kinaseegressmalariamicronemePlasmodium falciparum

Identifiers

PMID29487234
PMCPMC5829822
OpenAlexW2790331378

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.