Evidence map›Paper›PMID 29487145›Full record

ArticleGenetics2018

RNA Interference (RNAi) Screening in

Florian Heigwer, Fillip Port, Michael Boutros

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 120 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Ovary-Derived Signals Align Protein Appetite with Oogenesis.bioRxiv : the preprint server for biology · 2026
    Article
  5. Article
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  9. Review
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  15. Food science & nutrition · 2024
    Article
  16. Review
  17. Article
  18. Article
  19. A Cytological F1 RNAi Screen for Defects inbioRxiv : the preprint server for biology · 2024
    Article
  20. Article

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Florian HeigwerDivision of Signaling and Functional Genomics, German Cancer Research Center, and Department of Cell and Molecular Biology, Heidelberg University, Medical Faculty Mannheim, D-69120, Germany.ORCID 0000-0002-8230-1485
Fillip PortDivision of Signaling and Functional Genomics, German Cancer Research Center, and Department of Cell and Molecular Biology, Heidelberg University, Medical Faculty Mannheim, D-69120, Germany.ORCID 0000-0002-5157-4835
Michael BoutrosDivision of Signaling and Functional Genomics, German Cancer Research Center, and Department of Cell and Molecular Biology, Heidelberg University, Medical Faculty Mannheim, D-69120, Germany m.boutros@dkfz.de.ORCID 0000-0002-9458-817X
University Hospital Heidelberg · DEMedizinische Fakultät Mannheim

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the last decade, RNA interference (RNAi), a cellular mechanism that uses RNA-guided degradation of messenger RNA transcripts, has had an important impact on identifying and characterizing gene function. First discovered in

Indexed as

Genetic TestingRNA InterferenceRNA, Small InterferingAnimalsCell LineComputational BiologyCRISPR-Cas SystemsDrosophilaGenomeGenomicsHigh-Throughput Nucleotide SequencingSingle-Cell AnalysisSoftwareRNA, Small InterferingbioinformaticsDrosophilaFlyBookfunctional genomicsgenome engineeringhigh-throughput screeningimage-based screeningRNAi

Identifiers

PMID29487145
PMCPMC5844339
OpenAlexW2788780716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.