Evidence map›Paper›PMID 29487131›Full record

ArticleThe Journal of biological chemistry2018

Oxysterol-binding protein homologs mediate sterol transport from the endoplasmic reticulum to mitochondria in yeast.

Siqi Tian, Akinori Ohta, Hiroyuki Horiuchi, Ryouichi Fukuda

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Stay in touch with the endoplasmic reticulum.Science China. Life sciences · 2024
    Pooled it
  2. Article
  3. Article
  4. DVL, a Lectin fromAntibiotics (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Heterologous expression and functional characterization of the ligand-binding domain of oxysterol-binding protein from Aspergillus oryzae.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2019
    Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Siqi TianFrom the Department of Biotechnology, The University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-8657, Japan and.
Akinori OhtaDepartment of Biological Chemistry, College of Bioscience and Biotechnology, Chubu University, 1200 Matsumoto-cho, Kasugai, Aichi 487-8501, Japan.
Hiroyuki HoriuchiFrom the Department of Biotechnology, The University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-8657, Japan and.
Ryouichi FukudaFrom the Department of Biotechnology, The University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-8657, Japan and afukuda@mail.ecc.u-tokyo.ac.jp.
The University of Tokyo · JPChubu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sterols are present in eukaryotic membranes and significantly affect membrane fluidity, permeability, and microdomain formation. They are synthesized in the endoplasmic reticulum (ER) and transported to other organelles and the plasma membrane. Sterols play important roles in the biogenesis and maintenance of mitochondrial membranes. However, the mechanisms underlying ER-to-mitochondrion sterol transport remain to be identified. Here, using purified yeast membrane fractions enriched in ER and mitochondria, we show that the oxysterol-binding protein homologs encoded by the

Indexed as

Biological Transport, ActiveCarrier ProteinsCholesterolEndoplasmic ReticulumFatty Acid-Binding ProteinsGene DeletionMembrane ProteinsMitochondriaOxysterol Binding ProteinsReceptors, SteroidSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsCarrier ProteinsCholesterolFatty Acid-Binding ProteinsHES1 protein, S cerevisiaeKES1 protein, S cerevisiaeMembrane ProteinsOsh7 protein, S cerevisiaeOxysterol Binding ProteinsReceptors, SteroidSaccharomyces cerevisiae Proteinsendoplasmic reticulum (ER)ergosterolmitochondriamitochondrial membraneoxysterol-binding protein homologsteroltransportyeast

Identifiers

PMID29487131
PMCPMC5900766
OpenAlexW2791891846

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.