ArticleJournal of the American Heart Association2018
Prognostic Value of Early Postoperative Troponin T in Patients Undergoing Coronary Artery Bypass Grafting.
Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05562908 (Skeletonised Versus Pedicled Internal Thoracic Artery - A Randomised Study), which is not on this map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Skeletonised Versus Pedicled Internal Thoracic Artery - A Randomised Study
Who cites it
17 citing papers in PubMed, 36 citations in OpenAlex.
- Review
- Single-centre, single-blind, randomized, active-controlled phase-3 non-inferiority study to investigate the safety and efficacy of the cardioplegic solution Cardioplexol™.Frontiers in cardiovascular medicine · 2025Article
- How to harvest the left internal mammary artery-a randomized controlled trial.Interdisciplinary cardiovascular and thoracic surgery · 2024Article
- Chinese expert consensus on the diagnosis and treatment of coronary microvascular diseases (2023 Edition).MedComm · 2023Review
- Timing and threshold of high sensitive troponin T measurement for the prediction of mortality after cardiac surgery: a retrospective cohort analysis.Intensive care medicine experimental · 2023Article
- Defining Peri-Operative Myocardial Injury during Cardiac Surgery Using High-Sensitivity Troponin T.Journal of clinical medicine · 2023Article
- Prognostic value of high-sensitivity cardiac troponin I early after coronary artery bypass graft surgery.Journal of cardiothoracic surgery · 2022Article
- High-sensitivity cardiac troponin I after coronary artery bypass grafting for post-operative decision-making.European heart journal · 2022Article
- Saudi Heart Association Position Statement on the Use of Biomarkers for the Management of Heart Failure and Acute Coronary Syndrome.Journal of the Saudi Heart Association · 2022Article
- Coronary Microvascular Dysfunction Across the Spectrum of Cardiovascular Diseases: JACC State-of-the-Art Review.Journal of the American College of Cardiology · 2021Review
- Troponin T Elevation After Percutaneous Left Atrial Appendage Occlusion.Frontiers in cardiovascular medicine · 2021Article
- Release Profile of Cardiac Troponin T and Risk Factors of Postoperative Myocardial Injury in Patients Undergoing CABG.International journal of general medicine · 2021Article
- Association of early elevated cardiac troponin I concentration and longitudinal change after off-pump coronary artery bypass grafting and adverse events: a prospective cohort study.Journal of thoracic disease · 2020Article
- Analysis of Myocardial Ischemia Parameters after Coronary Artery Bypass Grafting with Minimal Extracorporeal Circulation and a Novel Microplegia versus Off-Pump Coronary Artery Bypass Grafting.Mediators of inflammation · 2020Article
- Single-center experience with the combination of Cardioplexol™ cardioplegia and MiECC for isolated coronary artery bypass graft procedures.Journal of thoracic disease · 2019Article
- Urinary Titin Is Increased in Patients After Cardiac Surgery.Frontiers in cardiovascular medicine · 2019Article
- Association between Contrast Media Volume and 1-Year Clinical Outcomes in Patients Undergoing Coronary Angiography.Chinese medical journal · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCardiac troponin T (cTnT) is elevated after coronary artery bypass grafting surgery. The aim of this study was to determine the association between cTnT elevations between 6 and 12 hours after coronary artery bypass grafting and in-hospital outcome. METHODS AND
resultsWe prospectively studied 1722 patients undergoing isolated coronary artery bypass grafting. We assessed the association between conventional cTnT (749 patients) and high-sensitivity cTnT (hs-cTnT; 973 patients) 6 to 12 hours postoperatively with in-hospital major adverse cardiac or cerebrovascular events (MACCE), a composite of all-cause death, myocardial infarction, or stroke. The prespecified secondary outcome was a safety composite of MACCE, resuscitation, intensive care unit readmission or admission ≥48 hours, inotrope or vasopressor use ≥24 hours, or new-onset renal insufficiency. Among patients with a conventional cTnT measurement, 92 experienced a MACCE (12%) and 146 experienced a safety composite event (19%). Likewise, for hs-cTnT, 114 experienced a MACCE (12%) and 153 experienced a safety composite event (16%). Compared with cTnT ≤200 ng/L, each 200-ng/L increment in cTnT was associated with a monotonous increase in the odds of MACCE and the safety composite outcome. Conventional and hs-cTnT demonstrated moderate discrimination for MACCE (areas under the fitted receiver operating characteristics curve, 0.72 and 0.77 for conventional and hs-cTnT, respectively) and the safety composite outcome (areas under the fitted receiver operating characteristics curve, 0.66 and 0.74 for conventional and hs-cTnT, respectively) and resulted in improved prognostic performance when added to the EuroSCORE. At a cutoff of 800 ng/L, conventional and hs-cTnT provided clinically relevant power to rule in MACCE and the safety composite outcome.
conclusionscTnT levels assessed between 6 and 12 hours after coronary artery bypass grafting identify patients at increased risk of MACCE or other complications.
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