Evidence map›Paper›PMID 29486813›Full record

ArticlePsychological medicine2018

Prevalence and heritability of body dysmorphic symptoms in adolescents and young adults: a population-based nationwide twin study.

Jesper Enander, Volen Z Ivanov, David Mataix-Cols, Ralf Kuja-Halkola, Brjánn Ljótsson, Sebastian Lundström, Ana Pérez-Vigil, Benedetta Monzani, Paul Lichtenstein, Christian Rück

Abstract readTwin Study
In one paragraph

Article in Psychological medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Genetics of OCD and Related Disorders; Searching for Shared Factors.Current topics in behavioral neurosciences · 2021
    Pooled it
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  4. Review
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  7. Body dysmorphic disorder.Nature reviews. Disease primers · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jesper EnanderDepartment of Clinical Neuroscience,Karolinska Institutet, Centre for Psychiatry Research,Stockholm,Sweden.
Volen Z IvanovDepartment of Clinical Neuroscience,Karolinska Institutet, Centre for Psychiatry Research,Stockholm,Sweden.
David Mataix-ColsDepartment of Clinical Neuroscience,Karolinska Institutet, Centre for Psychiatry Research,Stockholm,Sweden.
Ralf Kuja-HalkolaDepartment of Medical Epidemiology and Biostatistics,Karolinska Institutet,Stockholm,Sweden.
Brjánn LjótssonDepartment of Clinical Neuroscience,Karolinska Institutet, Centre for Psychiatry Research,Stockholm,Sweden.
Sebastian LundströmCentre for Ethics Law and Mental Health, University of Gothenburg,Gothenburg,Sweden.
Ana Pérez-VigilDepartment of Clinical Neuroscience,Karolinska Institutet, Centre for Psychiatry Research,Stockholm,Sweden.
Benedetta MonzaniInstitute of Psychiatry, Psychology & Neuroscience, King's College London,UK.
Paul LichtensteinDepartment of Medical Epidemiology and Biostatistics,Karolinska Institutet,Stockholm,Sweden.
Christian RückDepartment of Clinical Neuroscience,Karolinska Institutet, Centre for Psychiatry Research,Stockholm,Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBody dysmorphic disorder (BDD) usually begins during adolescence but little is known about the prevalence, etiology, and patterns of comorbidity in this age group. We investigated the prevalence of BDD symptoms in adolescents and young adults. We also report on the relative importance of genetic and environmental influences on BDD symptoms, and the risk for co-existing psychopathology.

methodsPrevalence of BDD symptoms was determined by a validated cut-off on the Dysmorphic Concerns Questionnaire (DCQ) in three population-based twin cohorts at ages 15 (n = 6968), 18 (n = 3738), and 20-28 (n = 4671). Heritability analysis was performed using univariate model-fitting for the DCQ. The risk for co-existing psychopathology was expressed as odds ratios (OR).

resultsThe prevalence of clinically significant BDD symptoms was estimated to be between 1 and 2% in the different cohorts, with a significantly higher prevalence in females (1.3-3.3%) than in males (0.2-0.6%). The heritability of body dysmorphic concerns was estimated to be 49% (95% CI 38-54%) at age 15, 39% (95% CI 30-46) at age 18, and 37% (95% CI 29-42) at ages 20-28, with the remaining variance being due to non-shared environment. ORs for co-existing neuropsychiatric and alcohol-related problems ranged from 2.3 to 13.2.

conclusionsClinically significant BDD symptoms are relatively common in adolescence and young adulthood, particularly in females. The low occurrence of BDD symptoms in adolescent boys may indicate sex differences in age of onset and/or etiological mechanisms. BDD symptoms are moderately heritable in young people and associated with an increased risk for co-existing neuropsychiatric and alcohol-related problems.

Indexed as

AdolescentAdultAlcohol-Related DisordersBody Dysmorphic DisordersCohort StudiesComorbidityFemaleHumansMaleMental DisordersPrevalenceSex FactorsSwedenYoung AdultBody dysmorphic disordercomorbidityheritabilityobsessive-compulsive disorderprevalencetwin study

Identifiers

PMID29486813
PMCPMC6236441

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.