ArticleEpidemiology and infection2018
Rheumatism and chronic fatigue, the two facets of post-chikungunya disease: the TELECHIK cohort study on Reunion island.
Article in Epidemiology and infection, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Recent research in myalgic encephalomyelitis/chronic fatigue syndrome: an evidence map.Health technology assessment (Winchester, England) · 2025Pooled it
- Clinical manifestations associated with the chronic phase of Chikungunya Fever: A systematic review of prevalence.PLoS neglected tropical diseases · 2025Pooled it
- Chikungunya virus infection in Indonesia: a systematic review and evolutionary analysis.BMC infectious diseases · 2019Pooled it
- Unveiling Clinical Phenotypes in Chronic Chikungunya Disease: Insights from a Brazilian Observational Study.Tropical medicine and infectious disease · 2026Article
- Considerations for epidemiological studies investigating emerging post-acute infection syndromes: Long Covid as a case study.EClinicalMedicine · 2026Review
- Acute Immunological Biomarkers for Predicting Chronic Rheumatologic Disease After Chikungunya Virus Infection.Tropical medicine and infectious disease · 2025Article
- Residual Symptoms and Quality of Life After Treated Lyme Neuroborreliosis: Case-Control Study (QoLYME).Open forum infectious diseases · 2025Article
- Chronic Rheumatologic Disease in Chikungunya Virus Fever: Results from a Cohort Study Conducted in Piedecuesta, Colombia.Tropical medicine and infectious disease · 2024Article
- Challenges to delivering evidence-based management for long COVID.BMJ evidence-based medicine · 2023Article
- Determinants of Health-Related Quality of Life in Chronic Chikungunya Disease in Guadeloupe.Pathogens (Basel, Switzerland) · 2022Article
- Unexplained post-acute infection syndromes.Nature medicine · 2022Review
- Post-COVID-19 syndrome: persistent neuroimaging changes and symptoms 9 months after initial infection.BMJ case reports · 2022Article
- The Female-Predominant Persistent Immune Dysregulation of the Post-COVID Syndrome.Mayo Clinic proceedings · 2022Article
- Predictors of Chronic Fatigue Syndrome and Mood Disturbance After Acute Infection.Frontiers in neurology · 2022Article
- Editorial: Current Insights Into Complex Post-infection Fatigue Syndromes With Unknown Aetiology: The Case of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Beyond.Frontiers in medicine · 2022Article
- Cytokine Deficiencies in Patients with Long-COVID.Journal of clinical & cellular immunology · 2022Article
- ["Long-haul COVID": An opportunity to address the complexity of post-infectious functional syndromes].La Revue de medecine interne · 2021Article
- Rediscovering the chikungunya virusBiomedica : revista del Instituto Nacional de Salud · 2021Review
- Post-Chikungunya Virus Infection Musculoskeletal Disorders: Syndromic Sequelae after an Outbreak.Tropical medicine and infectious disease · 2021Article
- Immunopathogenesis of alphaviruses.Advances in virus research · 2020Article
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Prolonged fatigue is increasingly reported among chikungunya virus (CHIKV)-infected populations. We investigated the relationships between CHIKV exposure, long-lasting rheumatic musculoskeletal pain (LRMSP) and chronic fatigue. 1094 participants (512 CHIKV seropositive and 582 seronegative) of the TELECHIK population-based cohort were analysed considering the duration of the manifestations throughout an average 2-year follow-up. Weighted prevalence rates and prevalence ratios for LRMSP, idiopathic chronic fatigue (ICF), and chronic fatigue syndrome (CFS)-like illness, both latter syndromes adapted from Centers for Disease Control (CDC)-1994/Fukuda criteria, were compared. Population attributable fractions (PAF) were estimated to assess the contribution of CHIKV infection to each of the three phenotypes. Among 362 adult subjects who had reported either rheumatic pain or fatigue at the onset of the infection, weighted prevalence rates of LRMSP, ICF and CFS-like illness were respectively of 32.9%, 38.7% and 23.9%, and of 8.7%, 8.5% and 7.4% among initially asymptomatic peers (P < 0.01, respectively). Each of the three outcomes was highly attributable to chikungunya (PAF of 43.2%, 36.2% and 41.0%, respectively). In the sub-cohort of CHIKV-infected subjects, LRMSP, ICF and CFS-like illness, which overlapped in 70%, accounted for 53% of the chronic manifestations. In addition to rheumatic disease, chronic fatigue could be considered in caring for patients with chronic chikungunya disease.
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